Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 7/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 7/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 7/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.42 |
| ▸ | PARP1 | P09874 | 3/20 | 0.36 |
| ▸ | TNKS | O95271 | 2/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24474404 | 1.00 | MAPK13 (0.42) | MAPK13MAPK12MAPK11MAPK14PARP1 | |
| SCHEMBL24474374 | 0.92 | MAPK13 (0.38) | MAPK13MAPK12MAPK11MAPK14PARP1 | |
| SCHEMBL24474400 | 0.90 | APLNR (0.39) | MAPK13MAPK12MAPK11MAPK14PARP1 | |
| SCHEMBL21542783 | 0.90 | KRAS (0.38) | MAPK13MAPK12MAPK11MAPK14TNKS | |
| SCHEMBL29700725 | 0.90 | KRAS (0.38) | MAPK13MAPK12MAPK11MAPK14TNKS | |
| SCHEMBL24474197 | 0.89 | BCAT1 (0.38) | MAPK13MAPK12MAPK11MAPK14KDM4E | |
| SCHEMBL24474245 | 0.88 | HCAR1 (0.44) | MAPK13MAPK12MAPK11MAPK14PARP1 | |
| SCHEMBL29700674 | 0.87 | KDM4E (0.35) | MAPK13MAPK12MAPK11MAPK14PARP1 | |
| SCHEMBL24474351 | 0.86 | MAPK13 (0.34) | MAPK13MAPK12MAPK11MAPK14HSP90AA1 | |
| SCHEMBL30487625 | 0.86 | MAPK13 (0.34) | MAPK13MAPK12MAPK11MAPK14HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116390919-A | Aromatic compound, preparation method and application thereof | 杭州多域生物技术有限公司 | 2023-07-04 | — | — | CN | disclosed |
| WO-2022111521-A1 | AROMATIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 杭州多域生物技术有限公司 | 2022-06-02 | — | — | WO | disclosed |