Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.48 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3509241 | 0.98 | DYRK1A (0.59) | DYRK1AKDM4EMAPTALDH1A1LMNA | |
| SCHEMBL2970653 | 0.79 | DYRK1A (0.60) | DYRK1AKDM4EMAPTALDH1A1LMNA | |
| SCHEMBL23594853 | 0.78 | DYRK1A (0.59) | DYRK1AKDM4EMAPTALDH1A1LMNA | |
| SCHEMBL28684906 | 0.77 | DYRK1A (0.57) | DYRK1AKDM4EMAPTALDH1A1LMNA | |
| SCHEMBL3508559 | 0.76 | DYRK1A (0.56) | DYRK1AKDM4EMAPTALDH1A1LMNA | |
| SCHEMBL22463059 | 0.76 | DYRK1A (1.00) | DYRK1AKDM4EMAPTALDH1A1LMNA | |
| SCHEMBL25035222 | 0.72 | DYRK1A (0.53) | DYRK1AKDM4EMAPTALDH1A1LMNA | |
| SCHEMBL23594892 | 0.72 | DYRK1A (0.52) | DYRK1AKDM4EMAPTALDH1A1LMNA | |
| SCHEMBL23729918 | 0.72 | DYRK1A (0.52) | DYRK1AKDM4EMAPTALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL3522469 | 0.71 | RAB9A (0.53) | DYRK1AKDM4EMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8273760-B2 | Indolo[3,2-c]quinoline compounds | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2012-09-25 | — | — | US | disclosed |
| US-8273760-B2 | Indolo[3,2-c]quinoline compounds | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2012-09-25 | — | — | US | disclosed |
| US-20100286163-A1 | INDOLO[3,2-C]QUINOLINE COMPOUNDS | Kaohsiung Medical Univeristy (TW) | 2010-11-11 | — | — | US | disclosed |
| US-20100286163-A1 | INDOLO[3,2-C]QUINOLINE COMPOUNDS | Kaohsiung Medical Univeristy (TW) | 2010-11-11 | — | — | US | disclosed |
| US-7763633-B2 | Indolo[3,2-c]quinoline compounds | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2010-07-27 | — | — | US | disclosed |
| US-20090298846-A1 | Indolo[3,2-c]quinoline Compounds | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298846-A1 | Indolo[3,2-c]quinoline Compounds | TERT, TERF2, CDKN1A | DYRK1A 4190/4885KDM4E 1179/4885MAPT 1245/4885 |
| US-20100286163-A1 | INDOLO[3,2-C]QUINOLINE COMPOUNDS | TERT, INMT, TERF2 | DYRK1A 2630/4885KDM4E 949/4885MAPT 905/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.