Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 18/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27215214 | 1.00 | HPGDS (0.36) | HPGDSIRAK4DGAT1 | |
| SCHEMBL18188139 | 0.81 | DGAT1 (0.33) | DGAT1 | |
| SCHEMBL29705469 | 0.81 | DGAT1 (0.33) | IRAK4DGAT1 | |
| SCHEMBL1565921 | 0.81 | DGAT1 (0.40) | IRAK4DGAT1 | |
| SCHEMBL19023260 | 0.81 | DGAT1 (0.33) | IRAK4DGAT1 | |
| SCHEMBL1417723 | 0.79 | DGAT1 (0.39) | HPGDSIRAK4DGAT1 | |
| SCHEMBL29930600 | 0.79 | HDAC8 (0.36) | DGAT1 | |
| SCHEMBL29705325 | 0.79 | DGAT1 (0.32) | DGAT1 | |
| SCHEMBL1565412 | 0.79 | DGAT1 (0.32) | DGAT1 | |
| SCHEMBL29705489 | 0.79 | NPC1 (0.33) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022159745-A1 | GCN2 MODULATING COMPOUNDS AND USES THEREOF | HIBERCELL, INC. (US) | 2022-07-28 | — | — | WO | disclosed |