SCHEMBL29706

SCHEMBL29706

CC(=O)CC([C]=O)C(C)=O

nearest known ligand 0.46

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
TDP1 Q9NUW8 2/20 0.46
TRPA1 O75762 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5299333 0.79 ALDH1A1 (0.43) ALDH1A1TDP1
SCHEMBL891222 0.78
SCHEMBL10700060 0.76
SCHEMBL10825100 0.74
SCHEMBL8532797 0.72
SCHEMBL1267259 0.72
SCHEMBL4749914 0.72
SCHEMBL4379448 0.72
SCHEMBL14764484 0.70 CA2 (0.40) ALDH1A1
SCHEMBL11331363 0.69 MAPT (0.45)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210300954-A1 IONIC TAGS FOR SYNTHESIS OF OLIGORIBONUCLEOTIDES THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIV (CA) 2021-09-30 US disclosed
US-11014948-B2 Ionic tags for synthesis of oligoribonucleotides THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) 2021-05-25 US disclosed
EP-2748176-B1 IONIC TAGS FOR SYNTHESIS OF OLIGORIBONUCLEOTIDES THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING / MCGILL UNIV (CA) 2019-04-17 EP disclosed
US-9920084-B2 Ionic tags for synthesis of oligoribonucleotides THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) 2018-03-20 US disclosed
CN-103237805-B The block synthesis of oligoribonucleotide 皇家学习促进学会/麦吉尔大学 2016-10-19 CN disclosed
US-20140256926-A1 Ionic Tags for Synthesis of Oligoribonucleotides HONG KONG POLYTECHNIC UNIVERSITY (HK) 2014-09-11 US disclosed
EP-2748176-A1 IONIC TAGS FOR SYNTHESIS OF OLIGORIBONUCLEOTIDES The Royal Institution for the Advancement of Learning / McGill University (CA) 2014-07-02 EP disclosed
CN-103889999-A Ionic tags for synthesis of oligoribonucleotides UNIV MCGILL 2014-06-25 CN disclosed
CN-103237805-A Block synthesis of oligoribonucleotides UNIV MCGILL 2013-08-07 CN disclosed
EP-2609107-A1 BLOCK SYNTHESIS OF OLIGORIBONUCLEOTIDES The Royal Institution for the Advancement of Learning / McGill University (CA) 2013-07-03 EP disclosed
WO-2013026142-A1 IONIC TAGS FOR SYNTHESIS OF OLIGORIBONUCLEOTIDES THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) 2013-02-28 WO disclosed
WO-2012024776-A1 BLOCK SYNTHESIS OF OLIGORIBONUCLEOTIDES THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) 2012-03-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11014948-B2 Ionic tags for synthesis of oligoribonucleotides RNGTT, OSTC, DTYMK ALDH1A1 3469/4885TDP1 811/4885TRPA1 3503/4885
US-20210300954-A1 IONIC TAGS FOR SYNTHESIS OF OLIGORIBONUCLEOTIDES RNGTT, OSTC, DTYMK ALDH1A1 3469/4885TDP1 811/4885TRPA1 3503/4885
US-20140256926-A1 Ionic Tags for Synthesis of Oligoribonucleotides RNGTT, OSTC, OSGEP ALDH1A1 3379/4885TDP1 752/4885TRPA1 3593/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.