Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.44 |
| ▸ | PDCD1LG2 | Q9BQ51 | 2/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.40 |
| ▸ | NMT2 | O60551 | 2/20 | 0.39 |
| ▸ | NMT1 | P30419 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 2/20 | 0.35 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.34 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.33 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38663399 | 1.00 | OPRM1 (0.44) | OPRM1OPRD1PDCD1LG2CD274NMT2 | |
| SCHEMBL30593912 | 0.95 | OPRM1 (0.43) | OPRM1OPRD1PDCD1LG2CD274NMT2 | |
| SCHEMBL29478036 | 0.88 | NMT1 (0.43) | OPRM1OPRD1NMT2NMT1QRFPR | |
| SCHEMBL29694604 | 0.87 | PDCD1LG2 (0.44) | OPRM1OPRD1PDCD1LG2CD274NMT2 | |
| SCHEMBL30019123 | 0.85 | NMT2 (0.38) | OPRM1OPRD1NMT2NMT1OPRK1 | |
| SCHEMBL29876444 | 0.84 | MME (0.39) | OPRM1OPRD1PDCD1LG2CD274OPRK1 | |
| SCHEMBL29473532 | 0.84 | MME (0.39) | OPRM1OPRD1PDCD1LG2CD274OPRK1 | |
| SCHEMBL31121552 | 0.84 | MME (0.39) | OPRM1OPRD1PDCD1LG2CD274OPRK1 | |
| SCHEMBL29866316 | 0.84 | TGFBR1 (0.44) | OPRM1OPRD1NMT2NMT1MME | |
| SCHEMBL29541562 | 0.84 | TGFBR1 (0.44) | OPRM1OPRD1NMT2NMT1MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114573686-A | Polypeptide containing disulfide bond and having serine protease activity inhibition function and application thereof | 中国医学科学院药物研究所 | 2022-06-03 | — | — | CN | disclosed |