SCHEMBL29473532

SCHEMBL29473532

C[C@@H](O)[C@H](NC(=O)CNC(=O)CNC(=O)CNC(=O)CN)C(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H](CO)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ MME P08473 5/20 0.39
▸ PRMT1 Q99873 1/20 0.37
▸ OPRM1 P35372 3/20 0.37
▸ OPRD1 P41143 3/20 0.37
▸ PDCD1LG2 Q9BQ51 1/20 0.36
▸ CD274 Q9NZQ7 1/20 0.36
▸ TGFBR1 P36897 3/20 0.36
▸ OPRK1 P41145 1/20 0.35
▸ QRFPR Q96P65 1/20 0.35
▸ OPRL1 P41146 2/20 0.34
▸ TERT O14746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29892461 1.00 MME (0.39) MMEPRMT1OPRM1OPRD1PDCD1LG2
SCHEMBL29876444 1.00 MME (0.39) MMEPRMT1OPRM1OPRD1PDCD1LG2
SCHEMBL31121552 1.00 MME (0.39) MMEPRMT1OPRM1OPRD1PDCD1LG2
SCHEMBL30593912 0.90 OPRM1 (0.43) MMEPRMT1OPRM1OPRD1PDCD1LG2
SCHEMBL31031477 0.85 ALDH1A1 (0.41) MMETERT
SCHEMBL6749006 0.85 TGFBR1 (0.42) MMEOPRM1OPRD1TGFBR1QRFPR
SCHEMBL31187165 0.85 TGFBR1 (0.42) MMEOPRM1OPRD1TGFBR1QRFPR
SCHEMBL17874144 0.85 TGFBR1 (0.42) MMEOPRM1OPRD1TGFBR1QRFPR
SCHEMBL6749004 0.85 TGFBR1 (0.42) MMEOPRM1OPRD1TGFBR1QRFPR
SCHEMBL1635449 0.85 TGFBR1 (0.42) MMEOPRM1OPRD1TGFBR1QRFPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12528872-B2 De novo binding domain containing polypeptides and uses thereof ARCELLX, INC. (US) 2026-01-20 — — US disclosed
US-20250382380-A1 D-DOMAIN CONTAINING POLYPEPTIDES AND USES THEREOF ARCELLX INC (US) 2025-12-18 — — US disclosed
US-20250353920-A1 DE NOVO BINDING DOMAIN CONTAINING POLYPEPTIDES AND USES THEREOF ARCELLX INC (US) 2025-11-20 — — US disclosed
US-20250353908-A1 D-DOMAIN CONTAINING POLYPEPTIDES AND USES THEREOF ARCELLX INC (US) 2025-11-20 — — US disclosed
US-20250320271-A1 D-DOMAIN CONTAINING POLYPEPTIDES AND USES THEREOF ARCELLX INC (US) 2025-10-16 — — US disclosed
US-12421291-B2 D-domain containing polypeptides and uses thereof ARCELLX, INC. (US) 2025-09-23 — — US disclosed
EP-4600353-A2 D-DOMAIN CONTAINING POLYPEPTIDES AND USES THEREOF Arcellx, Inc. (US) 2025-08-13 — — EP disclosed
EP-4596575-A2 MULTIFUNCTIONAL IMMUNE CELL THERAPIES Arcellx, Inc. (US) 2025-08-06 — — EP disclosed
US-12358995-B2 De novo binding domain containing polypeptides and uses thereof ARCELLX, INC. (US) 2025-07-15 — — US disclosed
EP-3710067-B1 D-DOMAIN CONTAINING POLYPEPTIDES AND USES THEREOF ARCELLX INC (US) 2025-07-02 — — EP disclosed
US-20240124605-A1 D-DOMAIN CONTAINING POLYPEPTIDES AND USES THEREOF ARCELLX, INC. 2024-04-18 — — US disclosed
US-11827716-B2 D-domain containing polypeptides and uses thereof ARCELLX, INC. (US) 2023-11-28 — — US disclosed
US-11730763-B2 Multifunctional immune cell therapies ARCELLX, INC. (US) 2023-08-22 — — US disclosed
US-20230250185-A1 D-DOMAIN CONTAINING POLYPEPTIDES AND USES THEREOF ARCELLX, INC. 2023-08-10 — — US disclosed
WO-2023086983-A1 D-DOMAIN CONTAINING POLYPEPTIDES AND USES THEREOF ARCELLX, INC. (US) 2023-05-19 — — WO disclosed
US-20230125550-A1 D-DOMAIN CONTAINING POLYPEPTIDES AND USES THEREOF ARCELLX, INC. 2023-04-27 — — US disclosed
US-11464803-B2 D-domain containing polypeptides and uses thereof ARCELLX, INC. (US) 2022-10-11 — — US disclosed
US-11377482-B2 D-domain containing polypeptides and uses thereof ARCELLX, INC. (US) 2022-07-05 — — US disclosed
US-11318165-B2 D-domain containing polypeptides and uses thereof ARCELLX, INC. (US) 2022-05-03 — — US disclosed
US-20220056105-A1 D-DOMAIN CONTAINING POLYPEPTIDES AND USES THEREOF ARCELLX, INC. 2022-02-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12421291-B2 D-domain containing polypeptides and uses thereof CD2BP2, PDIA6, BCAP31 MME 1268/4885PRMT1 3999/4885OPRM1 3522/4885
US-12528872-B2 De novo binding domain containing polypeptides and uses thereof CD2BP2, PHAX, VSIG8 MME 2197/4885PRMT1 1967/4885OPRM1 4022/4885
US-11464803-B2 D-domain containing polypeptides and uses thereof CD2BP2, PDIA6, BCAP31 MME 1268/4885PRMT1 3999/4885OPRM1 3522/4885
US-11730763-B2 Multifunctional immune cell therapies CD47, HAVCR2, ICOS MME 2859/4885PRMT1 589/4885OPRM1 4240/4885
US-20250320271-A1 D-DOMAIN CONTAINING POLYPEPTIDES AND USES THEREOF CD2BP2, PDIA6, BCAP31 MME 1268/4885PRMT1 3999/4885OPRM1 3522/4885
US-20230125550-A1 D-DOMAIN CONTAINING POLYPEPTIDES AND USES THEREOF CD2BP2, PDIA6, BCAP31 MME 1268/4885PRMT1 3999/4885OPRM1 3522/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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