SCHEMBL29706466

CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CN)[C@@H](C)O)[C@@H](C)CC)C(=O)N[C@@H](CS)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(=O)O)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	MAPK8	P45983	1/20	0.58

▸	MAPK9	P45984	1/20	0.58

▸	MAPK10	P53779	1/20	0.58

▸	EPHA2	P29317	2/20	0.53

▸	CXCR4	P61073	2/20	0.51

▸	APLNR	P35414	1/20	0.51

▸	NPY2R	P49146	8/20	0.51

▸	NPY4R	P50391	7/20	0.51

▸	NPY5R	Q15761	7/20	0.51

▸	NPY1R	P25929	6/20	0.51

▸	CALCR	P30988	2/20	0.50

▸	IL23R	Q5VWK5	1/20	0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30688070	0.98	MAPK8 (0.60)	MAPK8MAPK9MAPK10EPHA2CXCR4
SCHEMBL30688082	0.95	EPHA2 (0.59)	MAPK8MAPK9MAPK10EPHA2NPY2R
SCHEMBL30688077	0.91	MAPK8 (0.59)	MAPK8MAPK9MAPK10EPHA2NPY2R
SCHEMBL29706255	0.91	MAPK8 (0.56)	MAPK8MAPK9MAPK10IL23R
SCHEMBL17451635	0.90	APLNR (0.55)	MAPK8MAPK9MAPK10CXCR4APLNR
SCHEMBL29706178	0.90	MAPK8 (0.56)	MAPK8MAPK9MAPK10CXCR4NPY2R
SCHEMBL29706167	0.90	MAPK8 (0.56)	MAPK8MAPK9MAPK10CXCR4NPY2R
SCHEMBL30688083	0.90	MAPK8 (0.57)	MAPK8MAPK9MAPK10EPHA2APLNR
SCHEMBL29706257	0.89	MAPK8 (0.57)	MAPK8MAPK9MAPK10CXCR4NPY2R
SCHEMBL29706201	0.89	MAPK8 (0.59)	MAPK8MAPK9MAPK10EPHA2CXCR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20230416329-A1	A PEPTIDE WITH DISULFIDE BONDS AND INHIBITORY ACTIVITY AGAINST SERINE PROTEASES, DERIVED HYBRID PEPTIDES THEREOF, AND USES THEREOF	INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN)	2023-12-28	—	—	US	disclosed
CN-116615436-A	Disulfide bond-containing polypeptide with serine protease activity inhibiting function, hybrid peptide derived from disulfide bond-containing polypeptide and application of disulfide bond-containing polypeptide	中国医学科学院药物研究所	2023-08-18	—	—	CN	disclosed
WO-2022111713-A9	POLYPEPTIDE CONTAINING DISULFIDE BONDS AND CAPABLE OF INHIBITING ACTIVITY OF SERINE PROTEASE, DERIVED HYBRID PEPTIDE THEREOF, AND USE THEREOF	中国医学科学院药物研究所	2023-07-27	—	—	WO	disclosed
CN-114573686-A	Polypeptide containing disulfide bond and having serine protease activity inhibition function and application thereof	中国医学科学院药物研究所	2022-06-03	—	—	CN	disclosed
WO-2022111713-A1	POLYPEPTIDE CONTAINING DISULFIDE BONDS AND CAPABLE OF INHIBITING ACTIVITY OF SERINE PROTEASE, DERIVED HYBRID PEPTIDE THEREOF, AND USE THEREOF	中国医学科学院药物研究所	2022-06-02	—	—	WO	disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

Patent	Title	Text reads most about	Predicted target · text-rank
US-20230416329-A1	A PEPTIDE WITH DISULFIDE BONDS AND INHIBITORY ACTIVITY AGAINST SERINE PROTEASES, DERIVED HYBRID PEPTIDES THEREOF, AND USES THEREOF	VIP, SI, TMPRSS15	MAPK8 2212/4885MAPK9 1658/4885MAPK10 2052/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.