Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 2/20 | 0.50 |
| ▸ | SKP1 | P63208 | 2/20 | 0.50 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.50 |
| ▸ | BACE1 | P56817 | 6/20 | 0.48 |
| ▸ | KIT | P10721 | 1/20 | 0.48 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.47 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.47 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6266142 | 0.86 | SMARCA2 (0.49) | CKS1BSKP1SKP2BACE1KIT | |
| SCHEMBL19212321 | 0.84 | ALDH1A3 (0.46) | ALDH1A1MAPT | |
| SCHEMBL25402115 | 0.84 | SMARCA2 (0.54) | CKS1BSKP1SKP2BACE1KIT | |
| SCHEMBL31121084 | 0.84 | SMARCA2 (0.54) | CKS1BSKP1SKP2BACE1KIT | |
| SCHEMBL20818663 | 0.83 | CKS1B (0.58) | CKS1BSKP1SKP2BACE1KIT | |
| SCHEMBL4941483 | 0.82 | ALDH1A3 (0.57) | BACE1SMARCA2SMARCA4PBRM1GPR119 | |
| SCHEMBL17756944 | 0.82 | LMNA (0.47) | CKS1BSKP1SKP2BACE1SMARCA2 | |
| SCHEMBL29707378 | 0.82 | LMNA (0.47) | CKS1BSKP1SKP2BACE1SMARCA2 | |
| SCHEMBL12595780 | 0.82 | ALDH1A1 (0.59) | SMARCA2SMARCA4PBRM1GPR119ABCB1 | |
| SCHEMBL28931821 | 0.82 | NR1H2 (0.47) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3414252-B1 | THIENOPYRIDINE CARBOXAMIDES AS UBIQUITIN-SPECIFIC PROTEASE INHIBITORS | VALO HEALTH INC (US) | 2022-07-06 | — | — | EP | disclosed |