Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | SCD | O00767 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | BCL9 | O00512 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20971726 | 0.85 | MGLL (0.47) | GAAATMMGLLMAPTKMT2A | |
| SCHEMBL15077769 | 0.82 | ALDH1A1 (0.53) | GAAMAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL8568807 | 0.79 | MGLL (0.44) | GAAATMMGLLMAPTKMT2A | |
| SCHEMBL8574324 | 0.78 | MGLL (0.43) | GAAATMMGLLMAPTKMT2A | |
| SCHEMBL538117 | 0.73 | MAPT (0.59) | GAAMGLLMAPTKMT2AMEN1 | |
| SCHEMBL3062188 | 0.73 | LMNA (0.66) | GAAMAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL1912722 | 0.72 | MAPT (0.53) | GAAMGLLMAPTKMT2AMEN1 | |
| SCHEMBL3062186 | 0.72 | MGLL (0.45) | GAAATMMGLLMAPTKMT2A | |
| SCHEMBL3573967 | 0.72 | MAPT (0.66) | GAAATMMGLLMAPTKMT2A | |
| SCHEMBL594516 | 0.71 | SCD (0.69) | GAAMAPTKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3768272-B1 | JAK INHIBITORS | LIAO XIBIN (US) | 2025-07-30 | — | — | EP | disclosed |
| US-11365188-B2 | JAK inhibitors | LIAO XIBIN (US) | 2022-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11365188-B2 | JAK inhibitors | JAK1, JAK2, JAK3 | GAA 3844/4885ATM 384/4885MGLL 2902/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.