Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | BCL9 | O00512 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MYOC | Q99972 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8574324 | 0.85 | MGLL (0.43) | MGLLGAABCL9CTNNB1MAPT | |
| SCHEMBL8572623 | 0.84 | ALDH1A1 (0.48) | GAAMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL20971726 | 0.81 | MGLL (0.47) | MGLLGAABCL9CTNNB1MAPT | |
| SCHEMBL29708145 | 0.79 | GAA (0.50) | MGLLGAABCL9CTNNB1MAPT | |
| SCHEMBL8565123 | 0.74 | ALDH1A1 (0.49) | MAPTRAB9ANPC1LMNASMN1; SMN2 | |
| SCHEMBL8569581 | 0.73 | ALDH1A1 (0.44) | MAPTRAB9ANPC1LMNASMN1; SMN2 | |
| SCHEMBL15077546 | 0.72 | RAB9A (0.55) | GAAMAPTRAB9ANPC1LMNA | |
| SCHEMBL538117 | 0.71 | MAPT (0.59) | MGLLGAAMAPTRAB9ANPC1 | |
| SCHEMBL3062188 | 0.71 | LMNA (0.66) | GAAMAPTRAB9ANPC1LMNA | |
| SCHEMBL1912722 | 0.70 | MAPT (0.53) | MGLLGAABCL9CTNNB1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5705650-A | Process for preparing 1,2,4-thiadiazole derivatives | KATAYAMA SEIYAKUSYO CO., LTD. (JP) | 1998-01-06 | — | — | US | disclosed |
| US-5585494-A | Process for preparing 1,2,4-thiadiazole derivatives | KATAYAMA SEIYAKUSYO CO. LTD. (JP) | 1996-12-17 | — | — | US | disclosed |
| EP-0536900-A2 | Process for preparing 1,2,4-Thiadiazole Derivatives | KATAYAMA SEIYAKUSYO CO. Ltd. (JP) | 1993-04-14 | — | — | EP | disclosed |