Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA5 | P11021 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.40 |
| ▸ | DNPH1 | O43598 | 2/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.39 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.39 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.39 |
| ▸ | NT5E | P21589 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.38 |
| ▸ | ADK | P55263 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23216556 | 1.00 | HSPA5 (0.42) | HSPA5CYP1A2P2RY12DNPH1SIRT2 | |
| SCHEMBL29673052 | 0.82 | CYP1A2 (0.57) | CYP1A2ADORA3ADORA2AADORA1ADK | |
| SCHEMBL23216880 | 0.82 | CYP1A2 (0.57) | CYP1A2ADORA3ADORA2AADORA1ADK | |
| SCHEMBL25824151 | 0.82 | ADORA1 (0.43) | P2RY12ADORA3ADORA2AADORA1ADK | |
| SCHEMBL27056587 | 0.82 | ADORA1 (0.43) | P2RY12ADORA3ADORA2AADORA1ADK | |
| SCHEMBL23215186 | 0.75 | ADORA3 (0.47) | CYP1A2ADORA3ADORA2AADORA1ADK | |
| SCHEMBL29673046 | 0.75 | ADORA3 (0.47) | CYP1A2ADORA3ADORA2AADORA1ADK | |
| SCHEMBL14876593 | 0.73 | TYMP (0.41) | P2RY12SIRT2 | |
| SCHEMBL26107563 | 0.72 | P2RY12 (0.52) | P2RY12DNPH1P2RY2P2RY1P2RY6 | |
| SCHEMBL27056585 | 0.71 | ADK (0.59) | ADORA3ADORA2AADORA1ADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4404942-A2 | COMPOSITIONS FOR EDITING MECP2 TRANSCRIPTS AND METHODS THEREOF | Wave Life Sciences Ltd. (SG) | 2024-07-31 | — | — | EP | disclosed |
| EP-4240849-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | Wave Life Sciences Ltd. (SG) | 2023-09-13 | — | — | EP | disclosed |
| WO-2023049477-A2 | COMPOSITIONS FOR EDITING MECP2 TRANSCRIPTS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-03-30 | — | — | WO | disclosed |
| EP-4022059-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | Wave Life Sciences Ltd. (SG) | 2022-07-06 | — | — | EP | disclosed |