Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADK | P55263 | 6/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.39 |
| ▸ | AMD1 | P17707 | 1/20 | 0.38 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27056587 | 1.00 | ADORA1 (0.43) | ADORA1ADORA3ADORA2AADKPRMT6 | |
| SCHEMBL25824149 | 0.82 | ADK (0.59) | ADORA1ADORA3ADORA2AADK | |
| SCHEMBL27056585 | 0.82 | ADK (0.59) | ADORA1ADORA3ADORA2AADK | |
| SCHEMBL23216556 | 0.82 | HSPA5 (0.42) | ADORA1ADORA3ADORA2AADKP2RY12 | |
| SCHEMBL29709081 | 0.82 | HSPA5 (0.42) | ADORA1ADORA3ADORA2AADKP2RY12 | |
| SCHEMBL29313491 | 0.78 | PRMT6 (0.50) | ADORA1ADORA3PRMT6P2RY12BMPR1B | |
| SCHEMBL26553799 | 0.78 | MEN1 (0.54) | ADORA1ADORA3PRMT6P2RY12BMPR1B | |
| SCHEMBL25765124 | 0.78 | MEN1 (0.54) | ADORA1ADORA3PRMT6P2RY12BMPR1B | |
| SCHEMBL22930668 | 0.76 | PRMT6 (0.52) | ADORA1ADORA3PRMT6P2RY12BMPR1B | |
| SCHEMBL26347621 | 0.76 | BMPR1B (0.62) | ADORA1ADORA3P2RY12BMPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240026358-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2024-01-25 | — | — | US | disclosed |
| US-20230220384-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-07-13 | — | — | US | disclosed |