Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.45 |
| ▸ | KAT2B | Q92831 | 3/20 | 0.45 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL810629 | 0.83 | TSHR (0.67) | TSHRCYP3A4CYP1A2GPR35KAT2B | |
| SCHEMBL30006201 | 0.83 | TSHR (0.67) | TSHRCYP3A4CYP1A2GPR35KAT2B | |
| SCHEMBL294724 | 0.80 | TSHR (1.00) | TSHRCYP3A4GPR35KAT2BACHE | |
| SCHEMBL29431838 | 0.78 | CYP19A1 (0.49) | TSHRCYP3A4CYP19A1GPR35AAK1 | |
| SCHEMBL9197991 | 0.78 | AAK1 (0.60) | TSHRCYP3A4CYP19A1CYP1A2GPR35 | |
| SCHEMBL165733 | 0.78 | CYP19A1 (0.49) | TSHRCYP3A4CYP19A1GPR35AAK1 | |
| SCHEMBL557939 | 0.78 | TSHR (0.72) | TSHRCYP3A4GPR35KAT2BACHE | |
| SCHEMBL30947800 | 0.77 | AAK1 (0.48) | TSHRCYP3A4CYP19A1CYP1A2GPR35 | |
| SCHEMBL8142497 | 0.77 | MAOB (0.53) | TSHRCYP3A4LMNAACHEHSD17B10 | |
| SCHEMBL3804579 | 0.77 | GPR35 (0.59) | TSHRCYP3A4CYP19A1LMNAGPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12448368-B2 | Indole compounds as androgen receptor modulators | NIDO BIOSCIENCES, INC. (US) | 2025-10-21 | — | — | US | disclosed |
| WO-2025137639-A1 | MIXED SEROTONIN RECEPTOR BINDERS FOR TREATMENT OF PSYCHOTIC DISORDERS | DELIX THERAPEUTICS, INC. (US) | 2025-06-26 | — | — | WO | disclosed |
| US-20250122176-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES INC (US) | 2025-04-17 | — | — | US | disclosed |
| US-20250092021-A9 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES, INC. | 2025-03-20 | — | — | US | disclosed |
| US-20240390387-A1 | SULFONAMIDE OR SULFINAMIDE COMPOUND HAVING EFFECT OF INDUCING BRD4 PROTEIN DEGRADATION AND PHARMACEUTICAL USE THEREOF | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2024-11-28 | — | — | US | disclosed |
| US-12110293-B2 | Substituted triazolo quinoxaline derivatives | Grünenthal GmbH (DE) | 2024-10-08 | — | — | US | disclosed |
| US-12102641-B2 | Sulfonamide or sulfinamide compound having effect of inducing BRD4 protein degradation and pharmaceutical use thereof | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2024-10-01 | — | — | US | disclosed |
| CN-117800898-A | Carbazole compound and application thereof | 中国药科大学 | 2024-04-02 | — | — | CN | disclosed |
| US-11890288-B2 | Sulfonamide or sulfinamide compound having effect of inducing BRD4 protein degradation and pharmaceutical use thereof | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2024-02-06 | — | — | US | disclosed |
| US-11840541-B2 | Opioid receptor modulators | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2023-12-12 | — | — | US | disclosed |
| US-5219938-A | Reacting a living polymer of a conjugated diene with a tin or silicon compound and with a nitro compound, a phosphoryl chloride, aminosilane, an acrylamide or an aminovinylsilane; auto tires; impact strength; cold resistance; storage | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-06-15 | — | — | US | disclosed |
| US-5128416-A | Automobile tire treads | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-07-07 | — | — | US | disclosed |
| EP-0449649-A2 | Antineoplastic quinones and methods of using same | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1991-10-02 | — | — | EP | disclosed |
| EP-0444944-A2 | Synthesis and elucidation of azamitosene and iminoazamitosene | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1991-09-04 | — | — | EP | disclosed |
| US-5015692-A | Rubbers for tires having impact strength | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-05-14 | — | — | US | disclosed |
| US-5015742-A | Antitumor agents | ARIZONA BOARD OF REGENTS (US) | 1991-05-14 | — | — | US | disclosed |
| US-4957976-A | IMPROVED PROPERTIES FOR AUTOMOBILE TIRES, MODIFIED WITH PHOSPHORYL CHLORIDE | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1990-09-18 | — | — | US | disclosed |
| EP-0341496-A2 | Modified diene polymer rubbers | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-11-15 | — | — | EP | disclosed |
| EP-0270071-A2 | Process for preparing modified diene polymer rubbers | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-06-08 | — | — | EP | disclosed |
| US-4257915-A | USE IN PHOTOPOLYMERIZATION OF ETHYLENICALLY UNSATURATED MONOMERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250122176-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | AR, FSHR, NR5A1 | TSHR 509/4885CYP3A4 2783/4885CYP19A1 68/4885 |
| US-11890288-B2 | Sulfonamide or sulfinamide compound having effect of inducing BRD4 protein degradation and pharmaceutical use thereof | BRD4, BRD1, BRD2 | TSHR 3040/4885CYP3A4 3788/4885CYP19A1 3903/4885 |
| US-20250092021-A9 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | AR, FSHR, NR5A1 | TSHR 509/4885CYP3A4 2783/4885CYP19A1 68/4885 |
| US-12448368-B2 | Indole compounds as androgen receptor modulators | AR, FSHR, ADRB3 | TSHR 548/4885CYP3A4 2596/4885CYP19A1 114/4885 |
| US-12102641-B2 | Sulfonamide or sulfinamide compound having effect of inducing BRD4 protein degradation and pharmaceutical use thereof | BRD4, BRD1, BRD2 | TSHR 3040/4885CYP3A4 3788/4885CYP19A1 3903/4885 |
| US-20240390387-A1 | SULFONAMIDE OR SULFINAMIDE COMPOUND HAVING EFFECT OF INDUCING BRD4 PROTEIN DEGRADATION AND PHARMACEUTICAL USE THEREOF | BRD4, BRD1, BRD2 | TSHR 3040/4885CYP3A4 3788/4885CYP19A1 3903/4885 |
| US-11840541-B2 | Opioid receptor modulators | OPRM1, OPRL1, OPRD1 | TSHR 312/4885CYP3A4 390/4885CYP19A1 2306/4885 |
| US-12110293-B2 | Substituted triazolo quinoxaline derivatives | NR3C1, NR3C2, GRK5 | TSHR 179/4885CYP3A4 301/4885CYP19A1 147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.