Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.74 |
| ▸ | ELANE | P08246 | 3/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29709367 | 0.91 | EPHX2 (0.70) | EPHX2ELANEPIM1ALDH1A1CYP3A4 | |
| SCHEMBL16226676 | 0.87 | EPHX2 (0.86) | EPHX2ELANEPIM1ALDH1A1CYP3A4 | |
| SCHEMBL16932396 | 0.87 | EPHX2 (0.81) | EPHX2ELANEPIM1ALDH1A1CYP3A4 | |
| Chrysoobtusin SCHEMBL16226057 | 0.85 | EPHX2 (1.00) | EPHX2ELANEPIM1ALDH1A1CYP3A4 | |
| SCHEMBL31322006 | 0.81 | EPHX2 (1.00) | EPHX2ELANEPIM1ALDH1A1CYP3A4 | |
| SCHEMBL16226754 | 0.81 | EPHX2 (1.00) | EPHX2ELANEPIM1ALDH1A1CYP3A4 | |
| SCHEMBL29396060 | 0.81 | EPHX2 (1.00) | EPHX2ELANEPIM1ALDH1A1CYP3A4 | |
| SCHEMBL16226916 | 0.81 | ELANE (0.64) | EPHX2ELANEPIM1ALDH1A1CYP3A4 | |
| SCHEMBL3272698 | 0.81 | EPHX2 (0.68) | EPHX2ELANEPIM1ALDH1A1CYP3A4 | |
| SCHEMBL16227229 | 0.80 | MAPT (0.65) | EPHX2ELANEALDH1A1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11304927-B2 | Bioactive extract, fraction of Cassia occidentalis and formulation thereof for bone regeneration | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2022-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11304927-B2 | Bioactive extract, fraction of Cassia occidentalis and formulation thereof for bone regeneration | BMP4, BMP2, BMP1 | EPHX2 3231/4885ELANE 4141/4885PIM1 2182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.