Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 20/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29709894 | 1.00 | IRAK4 (0.48) | IRAK4 | |
| SCHEMBL24508596 | 1.00 | IRAK4 (0.48) | IRAK4 | |
| SCHEMBL20476036 | 0.84 | IRAK4 (0.54) | IRAK4 | |
| SCHEMBL29709731 | 0.80 | IRAK4 (0.43) | IRAK4 | |
| SCHEMBL30545154 | 0.80 | IRAK4 (0.44) | IRAK4 | |
| SCHEMBL31436622 | 0.77 | IRAK4 (0.61) | IRAK4 | |
| SCHEMBL26598605 | 0.77 | IRAK4 (0.61) | IRAK4 | |
| SCHEMBL24608428 | 0.74 | IRAK4 (0.72) | IRAK4 | |
| SCHEMBL29751427 | 0.74 | IRAK4 (0.72) | IRAK4 | |
| SCHEMBL21379161 | 0.74 | IRAK4 (0.57) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4271664-A1 | IRAK DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2023-11-08 | — | — | EP | disclosed |
| EP-4259128-A1 | IRAK DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2023-10-18 | — | — | EP | disclosed |
| CN-116867758-A | IRAK degradation agents and uses thereof | 凯麦拉医疗公司 | 2023-10-10 | — | — | CN | disclosed |
| WO-2022147465-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2022-07-07 | — | — | WO | disclosed |
| WO-2022125790-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2022-06-16 | — | — | WO | disclosed |