Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 2/20 | 0.66 |
| ▸ | CD44 | P16070 | 1/20 | 0.66 |
| ▸ | MAOB | P27338 | 1/20 | 0.66 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 3/20 | 0.46 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.43 |
| ▸ | PRCP | P42785 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,2,3,4-Tetrahydroisoquinoline SCHEMBL1788708 | 1.00 | PNMT (0.66) | PNMTCD44MAOBHTR2CKDM1A | |
| Trifluoroacetic Acid SCHEMBL5451230 | 0.91 | HTR2C (0.61) | PNMTCD44MAOBHTR2CKDM1A | |
| 1,2,3,4-Tetrahydroisoquinoline SCHEMBL6010101 | 0.87 | PNMT (0.79) | PNMTCD44MAOBHTR2CPRCP | |
| Trifluoroacetic Acid SCHEMBL4782632 | 0.87 | PNMT (0.43) | PNMTCD44MAOBKDM1A | |
| 1,2,3,4-Tetrahydroisoquinoline SCHEMBL4779021 | 0.85 | PNMT (0.76) | PNMTCD44MAOBHTR2CPRCP | |
| 1,2,3,4-Tetrahydroisoquinoline SCHEMBL6647088 | 0.84 | PNMT (0.73) | PNMTCD44MAOBHTR2CPRCP | |
| 1,2,3,4-Tetrahydroisoquinoline SCHEMBL4007316 | 0.84 | PNMT (0.73) | PNMTCD44MAOBHTR2CPRCP | |
| 1,2,3,4-Tetrahydroisoquinoline SCHEMBL19085 | 0.81 | PNMT (1.00) | PNMTCD44MAOBHTR2CASIC3 | |
| 1,2,3,4-Tetrahydroisoquinoline SCHEMBL29360217 | 0.81 | PNMT (1.00) | PNMTCD44MAOBHTR2CASIC3 | |
| 1,2,3,4-Tetrahydroisoquinoline SCHEMBL28236302 | 0.81 | PNMT (1.00) | PNMTCD44MAOBHTR2CASIC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025104152-A1 | MICROBIOCIDAL TETRAHYDROISOQUINOLINE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2025-05-22 | — | — | WO | disclosed |
| EP-4337207-A1 | COMPOUNDS AND METHODS FOR YAP/TEAD MODULATION AND INDICATIONS THEREFOR | Opna Bio SA (CH) | 2024-03-20 | — | — | EP | disclosed |
| CN-115974664-A | Synthesis method of 5-chloro-1-indanone | 合肥工业大学 | 2023-04-18 | — | — | CN | disclosed |
| WO-2022240966-A1 | COMPOUNDS AND METHODS FOR YAP/TEAD MODULATION AND INDICATIONS THEREFOR | OPNA IMMUNO-ONCOLOGY SA (CH) | 2022-11-17 | — | — | WO | disclosed |
| CN-108698992-B | 2-cyanoisoindoline derivatives for the treatment of cancer | 特殊治疗有限公司 | 2022-04-19 | — | — | CN | disclosed |