Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.61 |
| ▸ | PNMT | P11086 | 1/20 | 0.50 |
| ▸ | CD44 | P16070 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 9/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD1 | P21728 | 2/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD5 | P21918 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,2,3,4-Tetrahydroisoquinoline SCHEMBL1788708 | 0.91 | PNMT (0.66) | HTR2CPNMTCD44MAOBKDM1A | |
| 1,2,3,4-Tetrahydroisoquinoline SCHEMBL29710285 | 0.91 | PNMT (0.66) | HTR2CPNMTCD44MAOBKDM1A | |
| Trifluoroacetic Acid SCHEMBL4915477 | 0.81 | DRD2 (0.59) | HTR2CKDM1ADRD2DRD1HTR2B | |
| Trifluoroacetic Acid SCHEMBL4782632 | 0.80 | PNMT (0.43) | PNMTCD44MAOBKDM1ACES1 | |
| Trifluoroacetic Acid SCHEMBL2310563 | 0.79 | OPRD1 (0.57) | HTR2BHTR2ACES1 | |
| Succinic Acid SCHEMBL16464058 | 0.78 | HTR2C (0.64) | HTR2CPNMTCD44MAOBDRD2 | |
| Fumaric Acid SCHEMBL12504903 | 0.78 | HTR2C (0.64) | HTR2CPNMTCD44MAOBDRD2 | |
| Maleic Acid SCHEMBL29496807 | 0.78 | HTR2C (0.64) | HTR2CPNMTCD44MAOBDRD2 | |
| Fumaric Acid SCHEMBL12504899 | 0.78 | HTR2C (0.64) | HTR2CPNMTCD44MAOBDRD2 | |
| Malonic Acid SCHEMBL12504943 | 0.78 | HTR2C (0.64) | HTR2CPNMTCD44MAOBDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185089-A1 | Benzazepine derivatives for the treatment of neurological and psychiatric disorders | GLAXO GROUP LIMITED (GB) | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185089-A1 | Benzazepine derivatives for the treatment of neurological and psychiatric disorders | CNR2, GRIN2C, GRIN2B | HTR2C 12/4885PNMT 1171/4885CD44 4837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.