Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 8/20 | 0.46 |
| ▸ | GRIA3 | P42263 | 8/20 | 0.46 |
| ▸ | GRIA4 | P48058 | 7/20 | 0.46 |
| ▸ | GRIA2 | P42262 | 5/20 | 0.46 |
| ▸ | GRIK5 | Q16478 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.46 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.46 |
| ▸ | GRIK4 | Q16099 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2971633 | 0.91 | GRIA1 (0.47) | GRIA1GRIA3GRIA4GRIA2GRIK5 | |
| SCHEMBL2971635 | 0.91 | GRIA1 (0.47) | GRIA1GRIA3GRIA4GRIA2GRIK5 | |
| SCHEMBL158168 | 0.86 | MAPT (0.47) | GRIA1GRIA3GRIA4GRIA2GRIK5 | |
| SCHEMBL4626004 | 0.86 | MAPT (0.47) | GRIA1GRIA3GRIA4GRIA2GRIK5 | |
| SCHEMBL43843 | 0.86 | MAPT (0.47) | GRIA1GRIA3GRIA4GRIA2GRIK5 | |
| SCHEMBL11030460 | 0.78 | GRIA1 (0.53) | GRIA1GRIA3GRIA4GRIA2GRIK5 | |
| SCHEMBL6046222 | 0.78 | GRIA1 (0.53) | GRIA1GRIA3GRIA4GRIA2GRIK5 | |
| SCHEMBL5875640 | 0.78 | GRIA1 (0.53) | GRIA1GRIA3GRIA4GRIA2GRIK5 | |
| SCHEMBL5283079 | 0.77 | USP2 (0.47) | GRIA1GRIA3GRIA4GRIA2GRIK5 | |
| SCHEMBL5324038 | 0.77 | USP2 (0.47) | GRIA1GRIA3GRIA4GRIA2GRIK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210228723-A1 | METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE | Design Therapeutics, Inc. | 2021-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210228723-A1 | METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE | ZFX, F13B, GRN | GRIA1 1880/4885GRIA3 1651/4885GRIA4 2137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.