Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.38 |
| ▸ | CLK2 | P49760 | 2/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | CLK3 | P49761 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 3/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | PAK4 | O96013 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23147607 | 1.00 | TRPA1 (0.38) | TRPA1DYRK1ACLK2CLK4DYRK1B | |
| SCHEMBL16612853 | 0.81 | BRD4 (0.43) | DYRK1ACLK2CLK4DYRK1BCLK1 | |
| SCHEMBL3360828 | 0.79 | PRKCI (0.44) | DYRK1ACLK2CLK4DYRK1BCLK1 | |
| SCHEMBL23148049 | 0.79 | AXL (0.44) | DYRK1ACLK2CLK4DYRK1BCLK1 | |
| SCHEMBL29954439 | 0.79 | ALDH1A1 (0.38) | DYRK1ACLK2CLK4DYRK1BCLK1 | |
| SCHEMBL23147846 | 0.76 | TGFBR1 (0.39) | TRPA1DYRK1ACLK2CLK4DYRK1B | |
| SCHEMBL29722110 | 0.76 | TGFBR1 (0.39) | TRPA1DYRK1ACLK2CLK4DYRK1B | |
| SCHEMBL23147921 | 0.74 | BRD4 (0.43) | TRPA1DYRK1ABRD4NTRK1IGF1R | |
| SCHEMBL29721888 | 0.74 | BRD4 (0.43) | TRPA1DYRK1ABRD4NTRK1IGF1R | |
| SCHEMBL23147958 | 0.73 | TGFBR1 (0.41) | TRPA1DYRK1ACLK2CLK4DYRK1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4034108-A1 | AZAINDOLE CARBOXAMIDE COMPOUNDS FOR THE TREATMENT OF MYCOBACTERIAL INFECTIONS | The Global Alliance for TB Drug Development, Inc. (US) | 2022-08-03 | — | — | EP | disclosed |
| CN-114746090-A | Azaindole carboxamide compounds for the treatment of mycobacterial infections | 结核病药物开发全球联盟公司 | 2022-07-12 | — | — | CN | disclosed |