Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 12/20 | 0.64 |
| ▸ | TNKS2 | Q9H2K2 | 11/20 | 0.64 |
| ▸ | PARP1 | P09874 | 6/20 | 0.64 |
| ▸ | QTRT1 | Q9BXR0 | 1/20 | 0.61 |
| ▸ | GUSB | P08236 | 6/20 | 0.60 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.57 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.57 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.55 |
| ▸ | WNT3A | P56704 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6885282 | 0.80 | TNKS (0.93) | TNKSTNKS2PARP1GUSBPARP2 | |
| SCHEMBL15775207 | 0.79 | TNKS (1.00) | TNKSTNKS2PARP1GUSBPARP2 | |
| SCHEMBL8620410 | 0.78 | TNKS (0.83) | TNKSTNKS2PARP1GUSBPARP2 | |
| SCHEMBL103994 | 0.78 | QTRT1 (1.00) | TNKSTNKS2PARP1QTRT1GUSB | |
| SCHEMBL4505299 | 0.77 | TNKS (0.71) | TNKSTNKS2PARP1GUSBPARP2 | |
| SCHEMBL29784025 | 0.77 | TNKS (0.71) | TNKSTNKS2PARP1GUSBPARP2 | |
| SCHEMBL6124189 | 0.77 | TNKS (0.93) | TNKSTNKS2PARP1GUSBPARP2 | |
| SCHEMBL11712219 | 0.77 | ALDH1A1 (0.58) | NPC1RAB9AMAPTALDH1A1HPGD | |
| SCHEMBL29592833 | 0.76 | TNKS (1.00) | TNKSTNKS2PARP1GUSBPARP2 | |
| SCHEMBL258433 | 0.76 | TNKS (1.00) | TNKSTNKS2PARP1GUSBPARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110655505-B | 6- (2-amino-1H-benzo [ d ] imidazol-6-yl) quinazolin-4 (3H) -ones | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2022-06-21 | — | — | CN | claimed |