Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL23R | Q5VWK5 | 2/20 | 0.62 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.61 |
| ▸ | KISS1R | Q969F8 | 4/20 | 0.60 |
| ▸ | CXCR4 | P61073 | 6/20 | 0.60 |
| ▸ | NPY1R | P25929 | 1/20 | 0.59 |
| ▸ | NPY2R | P49146 | 1/20 | 0.59 |
| ▸ | NPY4R | P50391 | 1/20 | 0.59 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.59 |
| ▸ | CCKBR | P32239 | 1/20 | 0.57 |
| ▸ | MC4R | P32245 | 2/20 | 0.56 |
| ▸ | MC5R | P33032 | 2/20 | 0.56 |
| ▸ | MC3R | P41968 | 2/20 | 0.56 |
| ▸ | MC1R | Q01726 | 2/20 | 0.56 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29697189 | 0.91 | KISS1R (0.65) | IL23RC5AR1KISS1RCXCR4NPY1R | |
| SCHEMBL29973644 | 0.89 | KISS1R (0.66) | IL23RC5AR1KISS1RNPY1RNPY2R | |
| SCHEMBL30369815 | 0.88 | IL23R (0.65) | IL23RKISS1RCCKBR | |
| SCHEMBL31468796 | 0.88 | KISS1R (0.64) | IL23RC5AR1KISS1RNPY1RNPY2R | |
| SCHEMBL30272519 | 0.87 | CXCR4 (0.65) | C5AR1KISS1RCXCR4CXCL8 | |
| SCHEMBL30812404 | 0.87 | C5AR1 (0.61) | IL23RC5AR1CXCR4NPY1RNPY2R | |
| SCHEMBL31410855 | 0.87 | KISS1R (0.65) | IL23RC5AR1KISS1RNPY1RNPY2R | |
| SCHEMBL31105456 | 0.87 | NPY2R (0.71) | IL23RC5AR1CXCR4NPY1RNPY2R | |
| SCHEMBL30973980 | 0.87 | DPP3 (0.58) | KISS1RCXCR4CCKBR | |
| SCHEMBL30598997 | 0.87 | IL23R (0.62) | IL23RC5AR1KISS1RNPY1RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240026013-A2 | CX3CR1-BINDING POLYPEPTIDES COMPRISING IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS | ABLYNX N.V. (BE) | 2024-01-25 | — | — | US | claimed |
| CN-115925938-A | CX3CR1 binding polypeptides | 阿布林克斯有限公司 | 2023-04-07 | — | — | CN | claimed |
| EP-2820046-B1 | CX3CR1-BINDING POLYPEPTIDES | ABLYNX NV (BE) | 2022-06-15 | — | — | EP | claimed |
| US-20240279349-A2 | CX3CR1-BINDING POLYPEPTIDES COMPRISING IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS | ABLYNX N.V. (BE) | 2024-08-22 | — | — | US | disclosed |
| US-20240026013-A2 | CX3CR1-BINDING POLYPEPTIDES COMPRISING IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS | ABLYNX N.V. (BE) | 2024-01-25 | — | — | US | disclosed |
| CN-115925938-A | CX3CR1 binding polypeptides | 阿布林克斯有限公司 | 2023-04-07 | — | — | CN | disclosed |
| US-20230046772-A1 | CX3CR1-BINDING POLYPEPTIDES COMPRISING IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS | ABLYNX N.V. (BE) | 2023-02-16 | — | — | US | disclosed |
| EP-4050027-A2 | CX3CR1-BINDING POLYPEPTIDES | Ablynx N.V. (BE) | 2022-08-31 | — | — | EP | disclosed |
| CN-108610421-B | CX3CR1 binding polypeptides | 阿布林克斯有限公司 | 2022-08-19 | — | — | CN | disclosed |
| US-11384151-B2 | CX3CR1-binding polypeptides comprising immunoglobulin single variable domains | ABLYNX N.V. (BE) | 2022-07-12 | — | — | US | disclosed |
| EP-2820046-B1 | CX3CR1-BINDING POLYPEPTIDES | ABLYNX NV (BE) | 2022-06-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240026013-A2 | CX3CR1-BINDING POLYPEPTIDES COMPRISING IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS | CX3CR1, CCR5, CXCR3 | IL23R 343/4885C5AR1 160/4885KISS1R 434/4885 |
| US-20240279349-A2 | CX3CR1-BINDING POLYPEPTIDES COMPRISING IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS | CX3CR1, CCR5, CXCR3 | IL23R 343/4885C5AR1 160/4885KISS1R 434/4885 |
| US-20230046772-A1 | CX3CR1-BINDING POLYPEPTIDES COMPRISING IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS | CX3CR1, CCR5, CXCR3 | IL23R 343/4885C5AR1 160/4885KISS1R 434/4885 |
| US-11384151-B2 | CX3CR1-binding polypeptides comprising immunoglobulin single variable domains | CX3CR1, CCR5, CXCR3 | IL23R 343/4885C5AR1 160/4885KISS1R 434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.