Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21083704 | 1.00 | AGTR1 (0.53) | AGTR1 | |
| SCHEMBL30849998 | 0.92 | AGTR1 (0.60) | AGTR1 | |
| SCHEMBL21083794 | 0.92 | AGTR1 (0.60) | AGTR1 | |
| SCHEMBL29308429 | 0.86 | AGTR1 (0.52) | AGTR1 | |
| SCHEMBL29308431 | 0.86 | AGTR1 (0.53) | AGTR1 | |
| SCHEMBL21083712 | 0.83 | AGTR2 (0.60) | AGTR1 | |
| SCHEMBL29726837 | 0.83 | AGTR2 (0.60) | AGTR1 | |
| SCHEMBL21083987 | 0.83 | AGTR1 (0.49) | AGTR1 | |
| SCHEMBL29726849 | 0.83 | AGTR1 (0.49) | AGTR1 | |
| SCHEMBL1256316 | 0.81 | AGTR1 (0.58) | AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3478672-B1 | BIARYLMETHYL HETEROCYCLES | UNIV MONTREAL (CA) | 2024-04-10 | — | — | EP | disclosed |
| US-11407733-B2 | Biarylmethyl heterocycles | BRISTOL-MYERS SQUIBB COMPANY (US) | 2022-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11407733-B2 | Biarylmethyl heterocycles | ARRB1, ADRB2, ADRB1 | AGTR1 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.