SCHEMBL29736084

C[C@@H](O)[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CO)[C@@H](C)O)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	PDCD1LG2	Q9BQ51	1/20	0.46

▸	CD274	Q9NZQ7	1/20	0.46

▸	TFPI	P10646	1/20	0.45

▸	KEAP1	Q14145	2/20	0.43

▸	OPRL1	P41146	3/20	0.41

▸	PTH1R	Q03431	1/20	0.40

▸	RAMP3	O60896	3/20	0.40

▸	CALCR	P30988	3/20	0.40

▸	KISS1R	Q969F8	1/20	0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29736361	0.96	TFPI (0.44)	PDCD1LG2CD274TFPIKEAP1OPRL1
SCHEMBL29735980	0.95	KEAP1 (0.47)	TFPIKEAP1OPRL1
SCHEMBL29736417	0.91	TFPI (0.49)	TFPIOPRL1RAMP3CALCR
SCHEMBL29736056	0.91	TFPI (0.46)	TFPIKEAP1OPRL1RAMP3CALCR
SCHEMBL29736145	0.91	TFPI (0.46)	TFPIKEAP1OPRL1RAMP3CALCR
SCHEMBL29736168	0.90	KEAP1 (0.47)	TFPIKEAP1RAMP3CALCR
SCHEMBL30974217	0.89	PDCD1LG2 (0.45)	PDCD1LG2CD274KEAP1OPRL1KISS1R
SCHEMBL30443571	0.89	OPRM1 (0.46)	PDCD1LG2CD274KEAP1OPRL1
SCHEMBL29736066	0.89	KEAP1 (0.49)	TFPIKEAP1OPRL1
SCHEMBL30974356	0.88	PDCD1LG2 (0.46)	PDCD1LG2CD274KEAP1OPRL1KISS1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-11365217-B2	Peptides for treating telomere dysfunction-associated diseases and uses thereof	HANGZHOU DUANLI BIOTECHNOLOGY COMPANY LIMITED (CN)	2022-06-21	—	—	US	disclosed