SCHEMBL29736417

C[C@@H](O)[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CO)NC(=O)CN)[C@@H](C)O)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	TFPI	P10646	1/20	0.49

▸	IL23R	Q5VWK5	3/20	0.44

▸	GRIN2D	O15399	1/20	0.43

▸	GRIN3B	O60391	1/20	0.43

▸	GRIN1	Q05586	1/20	0.43

▸	GRIN2A	Q12879	1/20	0.43

▸	GRIN2B	Q13224	1/20	0.43

▸	GRIN2C	Q14957	1/20	0.43

▸	GRIN3A	Q8TCU5	1/20	0.43

▸	OPRL1	P41146	4/20	0.43

▸	VIPR1	P32241	1/20	0.42

▸	VIPR2	P41587	1/20	0.42

▸	RAMP3	O60896	4/20	0.41

▸	CALCR	P30988	4/20	0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29736322	0.96	TFPI (0.48)	TFPIIL23RGRIN2DGRIN3BGRIN1
SCHEMBL29736084	0.91	PDCD1LG2 (0.46)	TFPIOPRL1RAMP3CALCR
SCHEMBL30974512	0.89	TFPI (0.41)	TFPIOPRL1RAMP3CALCR
SCHEMBL29736145	0.89	TFPI (0.46)	TFPIOPRL1RAMP3CALCR
SCHEMBL29736056	0.89	TFPI (0.46)	TFPIOPRL1RAMP3CALCR
SCHEMBL29735980	0.89	KEAP1 (0.47)	TFPIIL23ROPRL1
SCHEMBL31182492	0.87	GRIN2D (0.49)	TFPIGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL29736361	0.86	TFPI (0.44)	TFPIOPRL1RAMP3CALCR
SCHEMBL29736155	0.86	TFPI (0.49)	TFPIOPRL1VIPR1
SCHEMBL29736243	0.85	PRMT1 (0.46)	TFPIIL23ROPRL1RAMP3CALCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-11365217-B2	Peptides for treating telomere dysfunction-associated diseases and uses thereof	HANGZHOU DUANLI BIOTECHNOLOGY COMPANY LIMITED (CN)	2022-06-21	—	—	US	disclosed