Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 4/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.47 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 2/20 | 0.44 |
| ▸ | KMO | O15229 | 1/20 | 0.42 |
| ▸ | MAP4K1 | Q92918 | 5/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL793754 | 0.99 | PIK3CD (0.46) | PIK3CDPIK3CAPIK3CGPIK3CBF10 | |
| SCHEMBL20124865 | 0.83 | PIK3CD (0.49) | PIK3CDPIK3CAPIK3CGPIK3CBF10 | |
| SCHEMBL29740650 | 0.83 | PIK3CD (0.49) | PIK3CDPIK3CAPIK3CGPIK3CBF10 | |
| SCHEMBL2940366 | 0.79 | MAP4K1 (0.50) | PIK3CDPIK3CAPIK3CGPIK3CBF10 | |
| SCHEMBL10272402 | 0.79 | ALDH1A1 (0.52) | PIK3CDPIK3CAPIK3CGPIK3CBF10 | |
| SCHEMBL20502398 | 0.79 | ALDH1A1 (0.48) | PIK3CDPIK3CAPIK3CGPIK3CBF10 | |
| SCHEMBL1438679 | 0.79 | PIK3CD (0.46) | PIK3CDPIK3CAPIK3CGPIK3CBF10 | |
| SCHEMBL13097259 | 0.79 | F10 (0.49) | PIK3CDPIK3CAPIK3CGPIK3CBF10 | |
| SCHEMBL198132 | 0.77 | PTGS2 (0.57) | F10PTGS2 | |
| SCHEMBL30706470 | 0.76 | ADRA2C (0.53) | PIK3CDPIK3CAPIK3CGKMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616466-A2 | PROCESS FOR DETERMINING THE SUITABILITY FOR DISTRIBUTION OF A BATCH OF A THIOPHENE-2-CARBOXAMIDE DERIVATIVE | Medichem, S.A. (ES) | 2013-07-24 | — | — | EP | claimed |
| WO-2012035057-A2 | PROCESS FOR DETERMINING THE SUITABILITY FOR DISTRIBUTION OF A BATCH OF A THIOPHENE-2-CARBOXAMIDE DERIVATIVE | MEDICHEM S.A. (ES) | 2012-03-22 | — | — | WO | claimed |
| EP-2616466-A2 | PROCESS FOR DETERMINING THE SUITABILITY FOR DISTRIBUTION OF A BATCH OF A THIOPHENE-2-CARBOXAMIDE DERIVATIVE | Medichem, S.A. (ES) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012035057-A2 | PROCESS FOR DETERMINING THE SUITABILITY FOR DISTRIBUTION OF A BATCH OF A THIOPHENE-2-CARBOXAMIDE DERIVATIVE | MEDICHEM S.A. (ES) | 2012-03-22 | — | — | WO | disclosed |