Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | CASP1 | P29466 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.38 |
| ▸ | HPGD | P15428 | 6/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | BPTF | Q12830 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 7/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29741052 | 0.72 | ALDH1A1 (0.35) | ALDH1A1HSD17B10MAPTKDM4EHPGD | |
| SCHEMBL26938659 | 0.71 | NLRP3 (0.37) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL29741173 | 0.70 | BPTF (0.36) | ALDH1A1HSD17B10MAPTMEN1KMT2A | |
| SCHEMBL13091633 | 0.65 | KDM4E (0.40) | ALDH1A1HSD17B10MAPTMEN1KMT2A | |
| SCHEMBL25837417 | 0.64 | KDM4E (0.37) | ALDH1A1HSD17B10MAPTMEN1KMT2A | |
| SCHEMBL21468537 | 0.63 | KDM4E (0.47) | ALDH1A1HSD17B10MAPTMEN1KMT2A | |
| SCHEMBL11038159 | 0.63 | ALDH1A1 (0.41) | ALDH1A1HSD17B10MAPTMEN1KMT2A | |
| SCHEMBL10891537 | 0.63 | BCL2L1 (0.46) | ALDH1A1MAPTHPGDL3MBTL1TDP1 | |
| SCHEMBL21625518 | 0.63 | ALDH1A1 (0.36) | ALDH1A1HSD17B10MAPTKMT2APOLB | |
| SCHEMBL23782914 | 0.62 | KDM4E (0.62) | ALDH1A1HSD17B10MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022155419-A1 | INDAZOLES AND AZAINDAZOLES AS LRRK2 INHIBITORS | ESCAPE Bio, Inc. (US) | 2022-07-21 | — | — | WO | disclosed |