Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.35 |
| ▸ | MAPT | P10636 | 8/20 | 0.35 |
| ▸ | GAA | P10253 | 5/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 6/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 2/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29741137 | 0.70 | AR (0.41) | ALDH1A1MAPTKDM4EHPGDNPSR1 | |
| SCHEMBL29740957 | 0.70 | ALDH1A1 (0.39) | BPTFALDH1A1HSD17B10MAPTGAA | |
| SCHEMBL25837417 | 0.69 | KDM4E (0.37) | BPTFALDH1A1HSD17B10MAPTGAA | |
| SCHEMBL11038159 | 0.68 | ALDH1A1 (0.41) | BPTFALDH1A1HSD17B10MAPTGAA | |
| SCHEMBL21499300 | 0.68 | NOS3 (0.39) | ALDH1A1MAPTGAAKDM4ELMNA | |
| SCHEMBL13091633 | 0.67 | KDM4E (0.40) | BPTFALDH1A1HSD17B10MAPTGAA | |
| SCHEMBL21468537 | 0.65 | KDM4E (0.47) | BPTFALDH1A1HSD17B10MAPTGAA | |
| SCHEMBL6250815 | 0.64 | NOS3 (0.42) | BPTFALDH1A1HSD17B10MAPTGAA | |
| SCHEMBL25986020 | 0.63 | AR (0.38) | ALDH1A1GAAKDM4EHPGD | |
| SCHEMBL28553563 | 0.63 | GAA (0.48) | ALDH1A1MAPTGAAKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022155419-A1 | INDAZOLES AND AZAINDAZOLES AS LRRK2 INHIBITORS | ESCAPE Bio, Inc. (US) | 2022-07-21 | — | — | WO | disclosed |