Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SQOR | Q9Y6N5 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CCR1 | P32246 | 2/20 | 0.38 |
| ▸ | CCR5 | P51681 | 2/20 | 0.38 |
| ▸ | CCR8 | P51685 | 2/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2977681 | 0.81 | ALDH1A1 (0.55) | SQORKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL12679741 | 0.77 | KDM4E (0.50) | SQORKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL819947 | 0.75 | KDM4E (0.48) | KDM4EALDH1A1HPGDMAPTPOLB | |
| SCHEMBL2979402 | 0.74 | KDM4E (0.45) | KDM4EALDH1A1HPGDMAPTPOLB | |
| SCHEMBL2974174 | 0.73 | SQOR (0.39) | SQORKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL18411239 | 0.71 | GRIA1 (0.44) | SQORKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL16501598 | 0.71 | PRKCI (0.39) | SQORKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL22660177 | 0.71 | PRKACA (0.35) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL12679834 | 0.70 | KDM4E (0.46) | SQORKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL12681335 | 0.70 | KDM4E (0.46) | SQORKDM4EALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2229377-A1 | 5-ALKYL/ALKENYL-3-CYANOPYRIDINES AS KINASE INHIBITORS | Wyeth LLC (US) | 2010-09-22 | — | — | EP | claimed |
| WO-2009076602-A1 | 5-ALKYL/ALKENYL-3-CYANOPYRIDINES AS KINASE INHIBITORS | WYETH (US) | 2009-06-18 | — | — | WO | claimed |