SCHEMBL297425

SCHEMBL297425

Nc1cc(SSc2ccc(C(=O)O)c(N)c2)ccc1C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.52
KDM4E B2RXH2 6/20 0.52
HPGD P15428 3/20 0.52
HSD17B10 Q99714 3/20 0.52
TDP1 Q9NUW8 4/20 0.50
CYP3A4 P08684 3/20 0.50
ALOX15 P16050 2/20 0.50
DTYMK P23919 1/20 0.49
PPM1B O75688 1/20 0.49
IDO1 P14902 1/20 0.47
KMT2A Q03164 4/20 0.45
GFER P55789 1/20 0.45
RXFP1 Q9HBX9 1/20 0.45
MAPT P10636 4/20 0.44
MCL1 Q07820 3/20 0.44
MEN1 O00255 3/20 0.44
THRB P10828 3/20 0.44
CYP1A2 P05177 2/20 0.44
RECQL P46063 2/20 0.44
CYP2C9 P11712 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3941969 0.88 KDM4E (0.52) ALDH1A1KDM4EHPGDHSD17B10TDP1
SCHEMBL1557874 0.84 MCL1 (0.59) ALDH1A1KDM4EHPGDHSD17B10TDP1
SCHEMBL9206001 0.80 DTYMK (0.58) ALDH1A1KDM4EHPGDHSD17B10TDP1
SCHEMBL24616726 0.80 LMNA (0.59) ALDH1A1KDM4EHPGDHSD17B10TDP1
SCHEMBL710309 0.76 PPM1B (0.75) ALDH1A1KDM4EHPGDHSD17B10TDP1
SCHEMBL715406 0.76 KDM4E (0.65) ALDH1A1KDM4EHPGDHSD17B10TDP1
SCHEMBL29436316 0.76 PPM1B (0.75) ALDH1A1KDM4EHPGDHSD17B10TDP1
SCHEMBL9174867 0.74 ALDH1A1 (0.55) ALDH1A1KDM4EHPGDHSD17B10TDP1
SCHEMBL6030346 0.74 KDM4E (0.63) ALDH1A1KDM4EHPGDHSD17B10TDP1
SCHEMBL23499274 0.74 PPM1B (0.79) ALDH1A1KDM4EHPGDHSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170110759-A1 SOLID ELECTROLYTE BASF SE (DE) 2017-04-20 US disclosed
EP-3120408-A1 SOLID ELECTROLYTE BASF SE (DE) 2017-01-25 EP disclosed
WO-2015140298-A1 SOLID ELECTROLYTE BASF SE (DE) 2015-09-24 WO disclosed
EP-1506240-B1 GRAFT POLYOLS PREPARED BY A CONTINUOUS PROCESS BASF CORP (US) 2012-03-14 EP disclosed
EP-1641852-B1 PROCESS FOR FORMATION OF PREFORMED STABILIZER POLYOLS BASF CORP (US) 2008-07-23 EP disclosed
US-7148288-B2 Process for formation of preformed stabilizer polyols BASF CORPORATION (US) 2006-12-12 US disclosed
EP-1641852-A1 PROCESS FOR FORMATION OF PREFORMED STABILIZER POLYOLS BASF Corporation (US) 2006-04-05 EP disclosed
EP-1506240-A1 GRAFT POLYOLS PREPARED BY A CONTINUOUS PROCESS BASF CORPORATION (US) 2005-02-16 EP disclosed
WO-2005003200-A1 PROCESS FOR FORMATION OF PREFORMED STABILIZER POLYOLS BASF CORPORATION (US) 2005-01-13 WO disclosed
US-20040266958-A1 Process for formation of preformed stabilizer polyols BASF CORPORATION 2004-12-30 US disclosed
US-4661531-A IN SITU FREE RADICAL POLYMERIZATION OF ETHYLENICALLY UNSATURATED MONOMER IN POLYOL BASF CORPORATION (US) 1987-04-28 US disclosed
US-4568705-A HIGH RESILIENT POLYETHER-AND ESTERURETHANES BASF WYANDOTTE CORPORATION (US) 1986-02-04 US disclosed
EP-0163188-A2 A graft polymer dispersion in a mixture of low molecular weight polyols and polyether polyols and polyurethane foams prepared therefrom BASF Corporation (US) 1985-12-04 EP disclosed
US-4555527-A POLYURETHANE FOAM BASF WYANDOTTE CORPORATION (US) 1985-11-26 US disclosed
US-4522976-A Graft polymer dispersion in a mixture of low molecular weight polyols and polyether polyols and polyurethane foams prepared therefrom BASF WYANDOTTE CORPORATION (US) 1985-06-11 US disclosed
US-4503207-A UNSATURATION-CONTAINING POLYOLS BASF WYANDOTTE CORPORATION (US) 1985-03-05 US disclosed
US-4458038-A ADDITION-CONDENSATION COPOLYMERS BASF WYANDOTTE CORPORATION (US) 1984-07-03 US disclosed
US-4454255-A 0.001 TO 0.09 MOLE OF INDUCED UNSATURATION PER MOLE OF POLYOL MIXTURE BASF WYANDOTTE CORPORATION (US) 1984-06-12 US disclosed
EP-0091036-A2 Process for the preparation of white graft polymer dispersions and flame-retardant polyurethane foams BASF Corporation (US) 1983-10-12 EP disclosed
US-4027090-A SYNERGISTIC MOLECULAR WEIGHT CONTROL STANDARD OIL COMPANY (US) 1977-05-31 US disclosed