Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 2/20 | 0.40 |
| ▸ | JAK1 | P23458 | 2/20 | 0.40 |
| ▸ | JAK3 | P52333 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | IKBKE | Q14164 | 5/20 | 0.38 |
| ▸ | TBK1 | Q9UHD2 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 5/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KLK1 | P06870 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26606609 | 0.96 | ALDH1A1 (0.42) | JAK2JAK1JAK3MAPTALDH1A1 | |
| SCHEMBL29746436 | 0.85 | ALDH1A1 (0.54) | MAPTALDH1A1TP53SMN1; SMN2L3MBTL1 | |
| SCHEMBL24570157 | 0.81 | ALDH1A1 (0.58) | MAPTALDH1A1TP53SMN1; SMN2L3MBTL1 | |
| SCHEMBL3258043 | 0.77 | GAA (0.44) | JAK2JAK1JAK3MAPTALDH1A1 | |
| SCHEMBL29746626 | 0.71 | L3MBTL1 (0.46) | MAPTSMN1; SMN2L3MBTL1GAAKDM4E | |
| SCHEMBL24570734 | 0.71 | MAPT (0.38) | JAK2JAK1JAK3MAPTALDH1A1 | |
| SCHEMBL29746328 | 0.69 | KDM4E (0.40) | MAPTALDH1A1TP53SMN1; SMN2MAPK1 | |
| SCHEMBL4411971 | 0.67 | GAA (0.42) | JAK2JAK1JAK3IKBKETBK1 | |
| SCHEMBL28965270 | 0.67 | JAK1 (0.48) | JAK2JAK1JAK3IKBKETBK1 | |
| SCHEMBL29746483 | 0.66 | L3MBTL1 (0.47) | MAPTALDH1A1SMN1; SMN2L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022138812-A1 | TETRAHYDRO THIENOPYRIDINE SULFONAMIDE COMPOUND | モジュラス株式会社 | 2022-06-30 | — | — | WO | disclosed |