SCHEMBL29746482

SCHEMBL29746482

NS(=O)(=O)c1cc2c(s1)NCNC2

nearest known ligand 0.43

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CA2 P00918 19/20 0.43
ADRA2A P08913 1/20 0.35
PNMT P11086 1/20 0.35
ADRA2B P18089 1/20 0.35
ADRA2C P18825 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29746502 0.83
SCHEMBL30096492 0.71 PNMT (0.54) PNMT
SCHEMBL6673498 0.71 PNMT (0.54) CA2ADRA2APNMTADRA2BADRA2C
SCHEMBL21192463 0.70 CYP2A6 (0.34)
SCHEMBL9429746 0.70 CA2 (0.62) CA2
Hydrochloric Acid SCHEMBL21962263 0.70 PNMT (0.53) CA2ADRA2APNMTADRA2BADRA2C
Hydrochloric Acid SCHEMBL9429811 0.69 CA2 (0.61) CA2
SCHEMBL10647462 0.68 PNMT (0.47) CA2ADRA2APNMTADRA2BADRA2C
SCHEMBL30565899 0.64 CA1 (0.58) CA2ADRA2APNMTADRA2BADRA2C
SCHEMBL9429535 0.64 CA2 (0.53) CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022138812-A1 TETRAHYDRO THIENOPYRIDINE SULFONAMIDE COMPOUND モジュラス株式会社 2022-06-30 WO disclosed