SCHEMBL29754573

SCHEMBL29754573

N=C(N)NCCC[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)CC(N)=O)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ IL23R Q5VWK5 19/20 0.62
▸ UTS2R Q9UKP6 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30592736 0.91 IL23R (0.62) IL23RUTS2R
SCHEMBL29576242 0.91 IL23R (0.59) IL23R
SCHEMBL30272483 0.90 IL23R (0.63) IL23RUTS2R
SCHEMBL29461988 0.90 IL23R (0.60) IL23R
SCHEMBL29868988 0.90 IL23R (0.60) IL23R
SCHEMBL29754641 0.90 NPY4R (0.54) IL23R
SCHEMBL30186443 0.89 KISS1R (0.60) UTS2R
SCHEMBL29461972 0.88 IL23R (0.63) IL23R
SCHEMBL30368198 0.87 NPY1R (0.56) IL23RUTS2R
SCHEMBL30636161 0.86 NPBWR1 (0.58) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022141500-A1 USE OF CELL PENETRATING PEPTIDE CAPABLE OF COMBINING WITH ACTIVE SUBSTANCE AND PROMOTING EFFICACY OF ACTIVE SUBSTANCE FOR SKINCARE 妍禾生医科技股份有限公司 2022-07-07 — — WO disclosed
EP-4023208-A1 TOPICAL COMPOSITIONS FOR SKIN COMPRISING A CELL PENETRATING PEPTIDE AND METHODS OF USING THE SAME ImDerma Laboratories Co., Ltd. (TW) 2022-07-06 — — EP disclosed
US-20220202943-A1 TOPICAL COMPOSITIONS FOR SKIN COMPRISING A CELL PENETRATING PEPTIDE AND METHODS OF USING THE SAME IMDERMA LABORATORIES CO.LTD. (TW) 2022-06-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220202943-A1 TOPICAL COMPOSITIONS FOR SKIN COMPRISING A CELL PENETRATING PEPTIDE AND METHODS OF USING THE SAME CUTA, NGLY1, SCNN1B IL23R 493/4885UTS2R 2040/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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