SCHEMBL29754641

SCHEMBL29754641

N=C(N)NCCC[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)CC(N)=O)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 13/20 0.54
▸ NPY1R P25929 8/20 0.54
▸ NPY2R P49146 6/20 0.54
▸ NPY5R Q15761 6/20 0.54
▸ IL23R Q5VWK5 5/20 0.49
▸ TFPI P10646 1/20 0.48
▸ VIPR1 P32241 1/20 0.47
▸ VIPR2 P41587 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30361584 0.91 NPY4R (0.57) NPY4RNPY1RNPY2RNPY5RIL23R
SCHEMBL30773467 0.90 NPY4R (0.55) NPY4RNPY1RNPY2RNPY5RTFPI
SCHEMBL29754573 0.90 IL23R (0.62) IL23R
SCHEMBL29530945 0.90 NPY4R (0.65) NPY4RNPY1RNPY2RNPY5R
SCHEMBL29531034 0.88 NPY4R (0.64) NPY4RNPY1RNPY2RNPY5R
SCHEMBL29449497 0.88 NPY4R (0.62) NPY4RNPY1RNPY2RNPY5RVIPR1
SCHEMBL30361666 0.88 NPY4R (0.63) NPY4RNPY1RNPY2RNPY5R
SCHEMBL31433352 0.87 NPY4R (0.59) NPY4RNPY1RNPY2RNPY5RTFPI
SCHEMBL31188458 0.87 NPY4R (0.65) NPY4RNPY1RNPY2RNPY5R
SCHEMBL30153268 0.87 NPY4R (0.65) NPY4RNPY1RNPY2RNPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022141500-A1 USE OF CELL PENETRATING PEPTIDE CAPABLE OF COMBINING WITH ACTIVE SUBSTANCE AND PROMOTING EFFICACY OF ACTIVE SUBSTANCE FOR SKINCARE 妍禾生医科技股份有限公司 2022-07-07 — — WO disclosed
EP-4023208-A1 TOPICAL COMPOSITIONS FOR SKIN COMPRISING A CELL PENETRATING PEPTIDE AND METHODS OF USING THE SAME ImDerma Laboratories Co., Ltd. (TW) 2022-07-06 — — EP disclosed
US-20220202943-A1 TOPICAL COMPOSITIONS FOR SKIN COMPRISING A CELL PENETRATING PEPTIDE AND METHODS OF USING THE SAME IMDERMA LABORATORIES CO.LTD. (TW) 2022-06-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220202943-A1 TOPICAL COMPOSITIONS FOR SKIN COMPRISING A CELL PENETRATING PEPTIDE AND METHODS OF USING THE SAME CUTA, NGLY1, SCNN1B NPY4R 660/4885NPY1R 1069/4885NPY2R 1549/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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