SCHEMBL29756201

SCHEMBL29756201

CC(Br)c1cccc(C=O)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
TYR P14679 1/20 0.42
UNG P13051 1/20 0.41
CYP2A6 P11509 1/20 0.39
EGFR P00533 1/20 0.37
SRC P12931 1/20 0.37
TRIM24 O15164 1/20 0.36
TRIM33 Q9UPN9 1/20 0.36
MAOA P21397 5/20 0.36
MAOB P27338 5/20 0.36
BRD4 O60885 1/20 0.36
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
ALDH1A3 P47895 1/20 0.34
TSHR P16473 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL727874 0.83 TYR (0.56) ALDH1A1TYRUNGCYP2A6SRC
SCHEMBL30291836 0.83 TYR (0.56) ALDH1A1TYRUNGCYP2A6SRC
SCHEMBL4951093 0.83 ALDH1A1 (0.54) ALDH1A1TYRUNGCYP2A6SRC
SCHEMBL8769118 0.80 TP53 (0.50) ALDH1A1TDP1TSHR
SCHEMBL27992416 0.80 ALDH1A1 (0.50) ALDH1A1TYRUNGCYP2A6SRC
SCHEMBL31124696 0.79 ALDH1A1 (0.48) ALDH1A1TYRUNGCYP2A6SRC
SCHEMBL2263076 0.79 ALDH1A1 (0.48) ALDH1A1TYRUNGCYP2A6SRC
SCHEMBL20931111 0.78 CNR2 (0.37) ALDH1A1TYRMAOAMAOBCA1
Benzene SCHEMBL28222842 0.78 UNG (0.44) ALDH1A1TYRUNGCYP2A6EGFR
SCHEMBL8897527 0.78 HDAC4 (0.37) ALDH1A1TYRCA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110627610-B Method for synthesizing alkyne by catalyzing asymmetric cross coupling 南方科技大学 2022-07-05 CN disclosed