Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 4/20 | 0.36 |
| ▸ | HTR2C | P28335 | 4/20 | 0.36 |
| ▸ | HRH1 | P35367 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14135291 | 0.82 | MAOA (0.42) | MAOBLMNAHTR2AHTR2CHRH1 | |
| SCHEMBL30883178 | 0.82 | MAOA (0.42) | MAOBLMNAHTR2AHTR2CHRH1 | |
| SCHEMBL2975635 | 0.75 | PLG (0.37) | MAOBLTB4RLTB4R2LMNAHTR2A | |
| SCHEMBL7169479 | 0.74 | LMNA (0.43) | MAOBLTB4RLTB4R2LMNACYP2C9 | |
| SCHEMBL350298 | 0.72 | DRD2 (0.60) | HTR2AHTR2CHRH1DRD2DRD3 | |
| SCHEMBL8314148 | 0.72 | DRD2 (0.60) | HTR2AHTR2CHRH1DRD2DRD3 | |
| SCHEMBL29960543 | 0.72 | DRD2 (0.60) | HTR2AHTR2CHRH1DRD2DRD3 | |
| SCHEMBL8314144 | 0.72 | DRD2 (0.60) | HTR2AHTR2CHRH1DRD2DRD3 | |
| SCHEMBL16257251 | 0.69 | STS (0.50) | MAOBHTR2AHTR2CHRH1CYP2C9 | |
| SCHEMBL28863772 | 0.68 | MAOB (0.48) | MAOBLTB4RLTB4R2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7776874-B2 | Amido compounds and their use as pharmaceuticals | INCYTE CORPORATION (US) | 2010-08-17 | — | — | US | disclosed |