Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALPL | P05186 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14705314 | 0.79 | ALDH1A1 (0.54) | ALDH1A1TP53TDP1KMT2APOLB | |
| SCHEMBL7079530 | 0.79 | ALDH1A1 (0.57) | ALDH1A1TP53TDP1KMT2APOLB | |
| SCHEMBL8312186 | 0.78 | KEAP1 (0.54) | ALDH1A1TDP1KMT2AMEN1HTT | |
| SCHEMBL790282 | 0.77 | NAMPT (0.65) | ALDH1A1TP53TDP1KMT2APOLB | |
| SCHEMBL31011102 | 0.75 | ALDH1A1 (0.50) | ALDH1A1TP53TDP1KMT2APOLB | |
| Hydrochloric Acid SCHEMBL20502487 | 0.75 | NAMPT (0.63) | ALDH1A1TP53TDP1KMT2APOLB | |
| SCHEMBL31011095 | 0.74 | LMNA (0.50) | ALDH1A1TP53TDP1KMT2APOLB | |
| SCHEMBL6739276 | 0.74 | LMNA (0.56) | ALDH1A1TP53TDP1KMT2APOLB | |
| SCHEMBL28464295 | 0.73 | LMNA (0.49) | ALDH1A1TP53TDP1KMT2APOLB | |
| SCHEMBL21536756 | 0.73 | ALDH1A1 (0.48) | ALDH1A1TP53TDP1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114728168-B | Triazole carbamate pyridylsulfonamides as LPA receptor antagonists and their use | 吉利德科学公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-114728168-A | Triazolecarbamate pyridylsulfonamides as LPA receptor antagonists and their use | 吉利德科学公司 | 2022-07-08 | — | — | CN | disclosed |