Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALPL | P05186 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL20502487 | 0.98 | NAMPT (0.63) | NAMPTALDH1A1TP53TDP1KEAP1 | |
| SCHEMBL6739276 | 0.81 | LMNA (0.56) | ALDH1A1TP53TDP1KMT2AMEN1 | |
| SCHEMBL21602344 | 0.81 | NAMPT (0.50) | NAMPTALDH1A1TP53TDP1KMT2A | |
| SCHEMBL7545177 | 0.80 | CA1 (0.57) | ALDH1A1TP53TDP1KMT2AMEN1 | |
| SCHEMBL28258314 | 0.80 | KMT2A (0.56) | NAMPTALDH1A1TP53TDP1KMT2A | |
| SCHEMBL3939566 | 0.80 | PTGS1 (0.54) | NAMPTALDH1A1TP53TDP1KMT2A | |
| SCHEMBL19700363 | 0.79 | ALDH1A1 (0.59) | ALDH1A1TP53TDP1KMT2AMEN1 | |
| SCHEMBL14705314 | 0.79 | ALDH1A1 (0.54) | ALDH1A1TP53TDP1KMT2AMEN1 | |
| SCHEMBL7079530 | 0.78 | ALDH1A1 (0.57) | NAMPTALDH1A1TP53TDP1KMT2A | |
| SCHEMBL28179572 | 0.78 | KMT2A (0.54) | NAMPTALDH1A1TP53TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 519 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230084927-A1 | GLUCOSE UPTAKE INHIBITORS AND USES THEREOF | METABOMED LTD. (IL) | 2023-03-16 | — | — | US | claimed |
| US-20040180889-A1 | Pin1-modulating compounds and methods of use thereof | PINTEX PHARMACEUTICALS, INC. | 2004-09-16 | — | — | US | claimed |
| WO-2003073999-A2 | PINI-MODULATING COMPOUNDS AND METHODS OF USE THEREOF | PINTEX PHARMACEUTICALS, INC. (US) | 2003-09-12 | — | — | WO | claimed |
| JP-5271191-A | — | — | None | — | — | JP | disclosed |
| US-20260078091-A1 | Piperidinone Derivatives as MDM2 Inhibitors for the Treatment of Cancer | AMGEN INC (US) | 2026-03-19 | — | — | US | disclosed |
| US-20250320213-A1 | Nitrogen-Containing Heterocyclic Compounds | PFIZER INC. (US) | 2025-10-16 | — | — | US | disclosed |
| US-20240300892-A1 | Piperidinone Derivatives as MDM2 Inhibitors for the Treatment of Cancer | AMGEN INC (US) | 2024-09-12 | — | — | US | disclosed |
| US-20240239792-A1 | MODULATORS OF BCL-2 OR BCL-2/BCL-XL AND USES THEREOF | ASIA VISION LIMITED (CN) | 2024-07-18 | — | — | US | disclosed |
| EP-3099304-B1 | CHROMAN DERIVATIVES AND THEIR USE IN THE TREATMENT OF GLAUCOMA | MAYO FOUND MEDICAL EDUCATION & RES (US) | 2024-07-17 | — | — | EP | disclosed |
| CN-117643634-A | Gold rod nanocomposite with bacterial targeting effect and preparation method and application thereof | 贵州医科大学 | 2024-03-05 | — | — | CN | disclosed |
| CN-117295717-A | LPA receptor antagonists and uses thereof | 吉利德科学公司 | 2023-12-26 | — | — | CN | disclosed |
| US-5494772-A | Heat-sensitive recording materials for infrared-laser recording comprising tricarbocyanine dye having at least two acidic groups | FUJI PHOTO FILM CO., LTD. (JP) | 1996-02-27 | — | — | US | disclosed |
| WO-1995000481-A1 | PIPERIDIN-1-YL-2,2-DIALKYLPROPANONEARYLSULFONAMIDE DERIVATIVES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1995-01-05 | — | — | WO | disclosed |
| JP-H05271191-A | AQUEOUS CHEMILUMINESCENCE SYSTEM | AMERICAN CYANAMID CO | 1993-10-19 | — | — | JP | disclosed |
| EP-0548616-A1 | Aqueous chemiluminescent systems | AMERICAN CYANAMID COMPANY (US) | 1993-06-30 | — | — | EP | disclosed |
| EP-0131302-B1 | IMIDAZOLIUM SALTS, INTERMEDIATES THERETO AND THEIR USE | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-01-29 | — | — | EP | disclosed |
| US-4766243-A | Electrophilic fluorination of aromatic compounds | OCCIDENTAL CHEMICAL CORPORATION (US) | 1988-08-23 | — | — | US | disclosed |
| US-4689341-A | Antiarrhythmic imidazoles | SCHERING A.G. (DE) | 1987-08-25 | — | — | US | disclosed |
| US-4613609-A | Antiarrhythmic imidazoliums | SCHERING A. G. (DE) | 1986-09-23 | — | — | US | disclosed |
| EP-0131302-A2 | Imidazolium salts, intermediates thereto and their use | SCHERING AKTIENGESELLSCHAFT (DE) | 1985-01-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240300892-A1 | Piperidinone Derivatives as MDM2 Inhibitors for the Treatment of Cancer | MDM2, TP53, CDKN1A | NAMPT 1367/4885ALDH1A1 332/4885TP53 2/4885 |
| US-20240239792-A1 | MODULATORS OF BCL-2 OR BCL-2/BCL-XL AND USES THEREOF | BCL2, BCL2L2, BCL2L1 | NAMPT 2670/4885ALDH1A1 3682/4885TP53 87/4885 |
| US-20260078091-A1 | Piperidinone Derivatives as MDM2 Inhibitors for the Treatment of Cancer | TP53, HIF1AN, MDM2 | NAMPT 3462/4885ALDH1A1 821/4885TP53 1/4885 |
| US-20250320213-A1 | Nitrogen-Containing Heterocyclic Compounds | HRH4, HNMT, NNT | NAMPT 26/4885ALDH1A1 2633/4885TP53 740/4885 |
| US-20230084927-A1 | GLUCOSE UPTAKE INHIBITORS AND USES THEREOF | SLC2A4, SLC2A1, SLC2A2 | NAMPT 705/4885ALDH1A1 1014/4885TP53 473/4885 |
| US-20040180889-A1 | Pin1-modulating compounds and methods of use thereof | PIN1, FKBP14, PIN4 | NAMPT 662/4885ALDH1A1 4434/4885TP53 129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.