Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 1/20 | 0.50 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.50 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24526689 | 1.00 | UCHL1 (0.50) | UCHL1USP30RIPK1NPC1LMNA | |
| SCHEMBL933084 | 0.83 | RIPK1 (0.50) | RIPK1NPC1LMNANPSR1ALDH1A1 | |
| SCHEMBL2695225 | 0.83 | RIPK1 (0.50) | RIPK1NPC1LMNANPSR1ALDH1A1 | |
| SCHEMBL8214939 | 0.83 | ROCK2 (0.53) | UCHL1USP30RIPK1NPC1LMNA | |
| SCHEMBL321027 | 0.83 | ROCK2 (0.53) | UCHL1USP30RIPK1NPC1LMNA | |
| SCHEMBL1653727 | 0.82 | NPC1 (0.52) | UCHL1USP30RIPK1NPC1LMNA | |
| SCHEMBL24527025 | 0.81 | UCHL1 (0.38) | UCHL1USP30RIPK1NR1H2NR1H3 | |
| SCHEMBL24527024 | 0.81 | CHRNB2 (0.41) | RIPK1 | |
| SCHEMBL21637242 | 0.81 | RIPK1 (0.47) | RIPK1NPC1LMNANPSR1ALDH1A1 | |
| SCHEMBL17067861 | 0.80 | RIPK1 (0.46) | RIPK1NPC1LMNANPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022129047-A2 | NOVEL MODULATORS OF THE NMDA RECEPTOR | H. LUNDBECK A/S (DK) | 2022-06-23 | — | — | WO | disclosed |