Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.51 |
| ▸ | RHEB | Q15382 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 7/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | BCR | P11274 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12475825 | 1.00 | TRPA1 (0.51) | TRPA1RHEBMEN1MAPK1KMT2A | |
| SCHEMBL3801229 | 0.81 | RHEB (0.54) | TRPA1RHEBMEN1MAPK1KMT2A | |
| SCHEMBL7079426 | 0.79 | RHEB (0.51) | TRPA1RHEBMEN1MAPK1KMT2A | |
| SCHEMBL26965661 | 0.79 | TRPA1 (0.56) | TRPA1RHEBMEN1MAPK1KMT2A | |
| SCHEMBL1499400 | 0.78 | RHEB (0.73) | TRPA1RHEBMEN1MAPK1KMT2A | |
| SCHEMBL1536356 | 0.77 | PARP1 (0.52) | KMT2ACYP1A2CYP3A4LMNAKDM4E | |
| SCHEMBL30681623 | 0.76 | AHR (0.57) | TRPA1RHEBMEN1MAPK1KMT2A | |
| SCHEMBL10926969 | 0.76 | HTR1A (0.45) | TRPA1RHEBMEN1MAPK1KMT2A | |
| SCHEMBL28658592 | 0.76 | SLC22A6 (0.50) | MEN1MAPK1KMT2AMAPTAHR | |
| SCHEMBL933005 | 0.75 | TRPA1 (0.46) | TRPA1RHEBMEN1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024201248-A1 | COMPOUNDS AND METHODS FOR DEGRADING GSPT1 | PIN THERAPEUTICS, INC. (KR) | 2024-10-03 | — | — | WO | disclosed |
| WO-2022133588-A1 | RNA VIRUS INHIBITOR COMPOUNDS AND USES THEREOF | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2022-06-30 | — | — | WO | disclosed |