Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 3/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | LIPE | Q05469 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL446891 | 0.78 | LPL (0.36) | LPLLIPGEGFRP2RX7CXCR2 | |
| SCHEMBL2370195 | 0.78 | LPL (0.40) | LPLLIPGEGFRP2RX7 | |
| SCHEMBL15817447 | 0.77 | EGFR (0.37) | LPLLIPGEGFRCXCR2LIPE | |
| SCHEMBL4561680 | 0.77 | LPL (0.35) | LPLLIPGEGFRCXCR2 | |
| SCHEMBL9941412 | 0.74 | LPL (0.33) | LPLLIPGEGFR | |
| SCHEMBL1780770 | 0.74 | LIPE (0.39) | LPLLIPGFFAR1CXCR2LIPE | |
| SCHEMBL22766301 | 0.74 | LPL (0.41) | LPLLIPGEGFRP2RX7FFAR1 | |
| SCHEMBL24683541 | 0.72 | TRPA1 (0.32) | — | |
| SCHEMBL5036984 | 0.72 | LPL (0.34) | LPLLIPGEGFRCXCR2 | |
| SCHEMBL29597659 | 0.72 | EGFR (0.36) | LPLLIPGEGFRCXCR2LIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4288424-A1 | NOVEL HETEROARYL-SUBSTITUTED IMIDAZOLE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2023-12-13 | — | — | EP | disclosed |
| WO-2022167631-A1 | NOVEL HETEROARYL-SUBSTITUTED IMIDAZOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2022-08-11 | — | — | WO | disclosed |