Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.65 |
| ▸ | THRB | P10828 | 3/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | G6PD | P11413 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.42 |
| ▸ | RAPGEF4 | Q8WZA2 | 8/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29764083 | 0.94 | CYP3A4 (0.71) | ALDH1A1CYP3A4TDP1THRBALOX15 | |
| SCHEMBL29709 | 0.94 | CYP3A4 (0.71) | ALDH1A1CYP3A4TDP1THRBALOX15 | |
| SCHEMBL11511767 | 0.89 | CYP3A4 (0.77) | ALDH1A1CYP3A4TDP1THRBALOX15 | |
| SCHEMBL3792803 | 0.85 | CYP3A4 (0.61) | ALDH1A1CYP3A4TDP1THRBALOX15 | |
| SCHEMBL22701365 | 0.82 | ALDH1A1 (0.72) | ALDH1A1CYP3A4TDP1THRBALOX15 | |
| SCHEMBL2127369 | 0.80 | ALDH1A1 (0.70) | ALDH1A1CYP3A4TDP1THRBALOX15 | |
| SCHEMBL30998047 | 0.80 | ALDH1A1 (0.70) | ALDH1A1CYP3A4TDP1THRBALOX15 | |
| SCHEMBL27438433 | 0.79 | ALDH1A1 (0.54) | ALDH1A1CYP3A4TDP1THRBALOX15 | |
| SCHEMBL8092870 | 0.78 | TDP1 (1.00) | ALDH1A1CYP3A4TDP1THRBALOX15 | |
| SCHEMBL28255467 | 0.78 | CYP3A4 (0.68) | ALDH1A1CYP3A4TDP1THRBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2231586-A1 | AZOMETHINE DIRECT DYES OR REDUCED PRECURSORS OF AZOMETHINE DIRECT DYES OBTAINED FROM 2-ALKYLRESORCINOLS, AND HAIR DYEING PROCESS USING THESE DYES OR PRECURSORS | L'Oréal (FR) | 2010-09-29 | — | — | EP | disclosed |
| WO-2009077391-A1 | AZOMETHINE DIRECT DYES OR REDUCED PRECURSORS OF AZOMETHINE DIRECT DYES OBTAINED FROM 2-ALKYLRESORCINOLS, AND HAIR DYEING PROCESS USING THESE DYES OR PRECURSORS | L'OREAL (FR) | 2009-06-25 | — | — | WO | disclosed |