Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA3 | P32297 | 2/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24466889 | 0.92 | CHRNB1 (0.53) | CHRNA3CHRNB4 | |
| SCHEMBL7366119 | 0.70 | CHRNA3 (0.52) | CHRNA3CHRNB4 | |
| SCHEMBL24760047 | 0.70 | CHRNB2 (0.63) | CHRNA3CHRNB4 | |
| Hydrochloric Acid SCHEMBL7839212 | 0.69 | CHRNB2 (0.51) | CHRNA3CHRNB4 | |
| Hydrochloric Acid SCHEMBL7460098 | 0.69 | CHRNB2 (0.51) | CHRNA3CHRNB4 | |
| SCHEMBL13066134 | 0.69 | SSTR4 (0.36) | — | |
| SCHEMBL13479963 | 0.68 | — | — | |
| SCHEMBL7272816 | 0.68 | LRRK2 (0.40) | — | |
| SCHEMBL7409979 | 0.68 | CHRNA3 (0.62) | CHRNA3CHRNB4 | |
| SCHEMBL13308144 | 0.68 | CHRNB2 (0.84) | CHRNA3CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4284802-A1 | SMALL MOLECULE INHIBITORS OF SALT INDUCIBLE KINASES | Janssen Biotech, Inc. (US) | 2023-12-06 | — | — | EP | claimed |
| WO-2022165530-A1 | SMALL MOLECULE INHIBITORS OF SALT INDUCIBLE KINASES | JANSSEN BIOTECH, INC. (US) | 2022-08-04 | — | — | WO | claimed |