Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.61 |
| ▸ | HTR3B | O95264 | 1/20 | 0.61 |
| ▸ | HTR3A | P46098 | 1/20 | 0.61 |
| ▸ | BACE1 | P56817 | 1/20 | 0.61 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.61 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2105330 | 1.00 | ALDH1A1 (0.61) | ALDH1A1HTR3EHTR3BHTR3ABACE1 | |
| SCHEMBL482225 | 0.84 | F7 (0.44) | ALDH1A1HTR3EHTR3BHTR3ABACE1 | |
| SCHEMBL1748354 | 0.79 | ALDH1A1 (0.66) | ALDH1A1HTR3EHTR3BHTR3ABACE1 | |
| SCHEMBL29822916 | 0.79 | ALDH1A1 (0.37) | ALDH1A1HTR3EHTR3BHTR3ABACE1 | |
| SCHEMBL28822617 | 0.79 | ALDH1A1 (0.37) | ALDH1A1HTR3EHTR3BHTR3ABACE1 | |
| SCHEMBL6630362 | 0.76 | ALDH1A1 (0.61) | ALDH1A1HTR3EHTR3BHTR3ABACE1 | |
| SCHEMBL9306275 | 0.76 | ALDH1A1 (0.61) | ALDH1A1HTR3EHTR3BHTR3ABACE1 | |
| SCHEMBL658809 | 0.76 | HTR3E (1.00) | ALDH1A1HTR3EHTR3BHTR3ABACE1 | |
| SCHEMBL13893030 | 0.76 | ALDH1A1 (0.35) | ALDH1A1HTR3EHTR3BHTR3ABACE1 | |
| SCHEMBL2106084 | 0.76 | ALPL (0.56) | METAP2METAP1CBFBAMY1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022165198-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2022-08-04 | — | — | WO | disclosed |