SCHEMBL2105330

SCHEMBL2105330

Sc1nc2ccc(Cl)cc2[nH]1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.61
HTR3E A5X5Y0 1/20 0.61
HTR3B O95264 1/20 0.61
HTR3A P46098 1/20 0.61
BACE1 P56817 1/20 0.61
HTR3D Q70Z44 1/20 0.61
HTR3C Q8WXA8 1/20 0.61
HPGD P15428 3/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
PSMB8 P28062 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
TP53 P04637 2/20 0.54
HSD17B10 Q99714 2/20 0.54
KDM4E B2RXH2 1/20 0.54
MEN1 O00255 1/20 0.54
CYP3A4 P08684 1/20 0.54
MAPT P10636 1/20 0.54
MAPK1 P28482 1/20 0.54
KMT2A Q03164 1/20 0.54
FTO Q9C0B1 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29770331 1.00 ALDH1A1 (0.61) ALDH1A1HTR3EHTR3BHTR3ABACE1
SCHEMBL482225 0.84 F7 (0.44) ALDH1A1HTR3EHTR3BHTR3ABACE1
SCHEMBL1748354 0.79 ALDH1A1 (0.66) ALDH1A1HTR3EHTR3BHTR3ABACE1
SCHEMBL29822916 0.79 ALDH1A1 (0.37) ALDH1A1HTR3EHTR3BHTR3ABACE1
SCHEMBL28822617 0.79 ALDH1A1 (0.37) ALDH1A1HTR3EHTR3BHTR3ABACE1
SCHEMBL6630362 0.76 ALDH1A1 (0.61) ALDH1A1HTR3EHTR3BHTR3ABACE1
SCHEMBL9306275 0.76 ALDH1A1 (0.61) ALDH1A1HTR3EHTR3BHTR3ABACE1
SCHEMBL658809 0.76 HTR3E (1.00) ALDH1A1HTR3EHTR3BHTR3ABACE1
SCHEMBL13893030 0.76 ALDH1A1 (0.35) ALDH1A1HTR3EHTR3BHTR3ABACE1
SCHEMBL2106084 0.76 ALPL (0.56) METAP2METAP1CBFBAMY1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 188 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122051380-A Application of additive in lithium battery electrolyte, electrolyte and lithium battery 中国科学院大连化学物理研究所 2026-05-15 CN claimed
CN-121394778-B Diaphragm and battery 珠海冠宇电池股份有限公司 2026-05-12 CN claimed
CN-121238173-B Diaphragm and battery 珠海冠宇电池股份有限公司 2026-05-12 CN claimed
CN-121282568-B Diaphragm and battery 珠海冠宇电池股份有限公司 2026-05-12 CN claimed
CN-119656892-A Hydrolyzed polyacrylonitrile-based zeolite imidazole framework membrane for ammonia separation and preparation method thereof 福州大学 2025-03-21 CN claimed
CN-116410733-A Composite material and preparation method thereof, photoelectric device and preparation method thereof, and display device TCL科技集团股份有限公司 2023-07-11 CN claimed
US-20220016099-A1 BENZIMIDAZOLE OR BENZOXAZOLE DERIVATIVES FOR PREVENTING AND TREATING CENTRAL NERVOUS SYSTEM DISEASE, DIABETES, AND COMPLICATIONS THEREOF TRINUERO (KR) 2022-01-20 US claimed
WO-2020116742-A1 BENZIMIDAZOLE OR BENZOXAZOLE DERIVATIVES FOR PREVENTING AND TREATING CENTRAL NERVOUS SYSTEM DISEASE, DIABETES, AND COMPLICATIONS THEREOF 주식회사 트리뉴로 2020-06-11 WO claimed
US-20040018983-A1 Antifungal compositions ACHILLION PHARMACEUTICALS, INC. 2004-01-29 US claimed
WO-2003055448-A2 ANTIFUNGAL COMPOSITIONS ACHILLION PHARMACEUTICALS, INC. (US) 2003-07-10 WO claimed
US-4587200-A Photopolymerizable composition comprising an acridine and a heterocyclic thiol compound as a photopolymerization initiator and a photographic process using said photopolymerizable composition FUJI PHOTO FILM CO., LTD. (JP) 1986-05-06 US claimed
US-4028272-A Process of polymerization of conjugated diolefins using iron catalysts and sulfur ligands THE GOODYEAR TIRE & RUBBER COMPANY (US) 1977-06-07 US claimed
CN-122051380-A Application of additive in lithium battery electrolyte, electrolyte and lithium battery 中国科学院大连化学物理研究所 2026-05-15 CN disclosed
CN-121238173-B Diaphragm and battery 珠海冠宇电池股份有限公司 2026-05-12 CN disclosed
CN-121282568-B Diaphragm and battery 珠海冠宇电池股份有限公司 2026-05-12 CN disclosed
CN-121261064-B Battery cell 珠海冠宇电池股份有限公司 2026-05-12 CN disclosed
US-4069259-A Process for preparing organic disulfides ALLIED CHEMICAL CORPORATION (US) 1978-01-17 US disclosed
US-4028272-A Process of polymerization of conjugated diolefins using iron catalysts and sulfur ligands THE GOODYEAR TIRE & RUBBER COMPANY (US) 1977-06-07 US disclosed
US-3976769-A INSECTICIDE AIRWICK INDUSTRIES, INC. (US) 1976-08-24 US disclosed
US-3936432-A AND SULFUR LIGANDSS- OR O-CONTAINING LIGANDS WITH IMINE OR IMIDAZOLE GROUPS; DITHIOOXAMIDES THE GOODYEAR TIRE & RUBBER COMPANY (US) 1976-02-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040018983-A1 Antifungal compositions CNBP, ERG28, AEBP2 ALDH1A1 4343/4885HTR3E 4073/4885HTR3B 4277/4885
US-20220016099-A1 BENZIMIDAZOLE OR BENZOXAZOLE DERIVATIVES FOR PREVENTING AND TREATING CENTRAL NERVOUS SYSTEM DISEASE, DIABETES, AND COMPLICATIONS THEREOF KEAP1, SLC5A1, GCLC ALDH1A1 161/4885HTR3E 4245/4885HTR3B 3728/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.