Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | F2RL1 | P55085 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2968176 | 0.85 | MAOB (0.39) | MAOBTP53CYP3A4CYP2D6MRGPRX4 | |
| SCHEMBL2653758 | 0.75 | TAAR1 (0.38) | TP53CYP3A4TSHRADRA2AADRA2B | |
| SCHEMBL18217414 | 0.68 | MAOB (0.47) | MAOBTP53CYP3A4MRGPRX4ACHE | |
| SCHEMBL11210106 | 0.68 | MAOB (0.47) | MAOBTP53CYP3A4MRGPRX4ACHE | |
| SCHEMBL15914597 | 0.68 | SLC1A2 (0.43) | MAOBCYP2D6MAOA | |
| SCHEMBL3978159 | 0.68 | CYP3A4 (0.38) | MAOBTP53CYP3A4F2RL1TSHR | |
| SCHEMBL27984245 | 0.67 | TAAR1 (0.44) | MAOBCYP2D6TSHRADRA2AADRA2B | |
| Trifluoroacetic Acid SCHEMBL6220279 | 0.67 | ADRA2A (0.39) | CYP3A4CYP2D6TSHRADRA2AADRA2B | |
| SCHEMBL14886811 | 0.66 | MAOB (0.42) | MAOBTP53CYP3A4TSHRMRGPRX4 | |
| SCHEMBL10463711 | 0.66 | TAAR1 (0.64) | MAOBCYP2D6TSHRADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7776900-B2 | Benzimidazole derivatives and their use for modulating the GABAAreceptor complex | NEUROSEARCH A/S (DK) | 2010-08-17 | — | — | US | disclosed |
| US-20090030018-A1 | Benzimidazole derivatives and their use for modulating the gabaalpha receptor complex | ANIONA APS (DK) | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090030018-A1 | Benzimidazole derivatives and their use for modulating the gabaalpha receptor complex | GABRB2, GABRB1, GABRB3 | MAOB 164/4885TP53 4872/4885CYP3A4 628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.