Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 4/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 6/20 | 0.41 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29772026 | 0.96 | FOLH1 (0.45) | FOLH1OPRM1OPRD1EGFRGLO1 | |
| SCHEMBL29771973 | 0.94 | FOLH1 (0.44) | FOLH1OPRM1OPRD1EGFRGLO1 | |
| SCHEMBL29772029 | 0.94 | OPRM1 (0.46) | FOLH1OPRM1OPRD1EGFROPRK1 | |
| SCHEMBL31194150 | 0.91 | FOLH1 (0.49) | FOLH1OPRM1OPRD1EGFRGLO1 | |
| SCHEMBL29772030 | 0.91 | EGFR (0.47) | FOLH1OPRM1OPRD1EGFROPRK1 | |
| SCHEMBL29360974 | 0.90 | OPRM1 (0.46) | FOLH1OPRM1OPRD1EGFROPRK1 | |
| SCHEMBL30903455 | 0.89 | FOLH1 (0.60) | FOLH1BACE1BACE2 | |
| SCHEMBL29771977 | 0.89 | EGFR (0.49) | FOLH1OPRM1OPRD1EGFROPRK1 | |
| SCHEMBL30099566 | 0.88 | FOLH1 (0.45) | FOLH1GLO1PTGS1GSTK1NOD1 | |
| SCHEMBL30381811 | 0.88 | FOLH1 (0.46) | FOLH1OPRM1OPRD1EGFRGLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12221494-B2 | Short synthetic peptides and their uses for treating retinal degenerative diseases and/or tissue injuries | MACKAY MEMORIAL HOSPITAL (TW) | 2025-02-11 | — | — | US | disclosed |
| US-20220204559-A1 | SHORT SYNTHETIC PEPTIDES AND THEIR USES FOR TREATING RETINAL DEGENERATIVE DISEASES AND/OR TISSUE INJURIES | MACKAY MEMORIAL HOSPITAL (TW) | 2022-06-30 | — | — | US | disclosed |