Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCB | P05771 | 7/20 | 0.65 |
| ▸ | CDK4 | P11802 | 3/20 | 0.65 |
| ▸ | CCND1 | P24385 | 3/20 | 0.65 |
| ▸ | CDK2 | P24941 | 3/20 | 0.65 |
| ▸ | PRKCA | P17252 | 2/20 | 0.65 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.65 |
| ▸ | PRKACA | P17612 | 2/20 | 0.65 |
| ▸ | PRKACG | P22612 | 2/20 | 0.65 |
| ▸ | PRKACB | P22694 | 2/20 | 0.65 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.65 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.65 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.65 |
| ▸ | ABL1 | P00519 | 2/20 | 0.65 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.65 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.65 |
| ▸ | PRKCG | P05129 | 1/20 | 0.65 |
| ▸ | CDK1 | P06493 | 1/20 | 0.65 |
| ▸ | PIM1 | P11309 | 1/20 | 0.65 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.65 |
| ▸ | PRKCH | P24723 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2193383 | 1.00 | PRKCB (0.65) | PRKCBCDK4CCND1CDK2PRKCA | |
| Indazole SCHEMBL28147212 | 0.85 | PRKCB (0.49) | PRKCBCDK4CCND1CDK2PRKCA | |
| Ro-316233 SCHEMBL624896 | 0.79 | PRKCB (1.00) | PRKCBCDK4CCND1CDK2PRKCA | |
| Ro-316233 SCHEMBL29373011 | 0.79 | PRKCB (1.00) | PRKCBCDK4CCND1CDK2PRKCA | |
| SCHEMBL7951074 | 0.79 | PTPN1 (0.73) | PRKCBCDK4CCND1CDK2PRKCA | |
| SCHEMBL27866859 | 0.79 | PIK3CD (0.45) | PRKCBCDK4CCND1CDK2PRKCA | |
| SCHEMBL5879200 | 0.78 | CDK4 (0.46) | PRKCBCDK4CCND1CDK2PRKCA | |
| SCHEMBL5879319 | 0.78 | CDK4 (0.49) | PRKCBCDK4CCND1CDK2PRKCA | |
| SCHEMBL5879170 | 0.78 | F7 (0.45) | PRKCBCDK4CCND1CDK2PRKCA | |
| SCHEMBL5879255 | 0.78 | IGF1R (0.50) | PRKCBCDK4CCND1CDK2PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240034799-A1 | METHODS AND SYSTEMS OF STRATIFYING INFLAMMATORY DISEASE PATIENTS | CEDARS SINAI MEDICAL CENTER (US) | 2024-02-01 | — | — | US | disclosed |
| US-20230279491-A1 | TREATMENTS FOR A SUB-POPULATION OF INFLAMMATORY BOWEL DISEASE PATIENTS | CEDARS-SINAI MEDICAL CENTER | 2023-09-07 | — | — | US | disclosed |
| US-11578060-B2 | JAK3 selective inhibitor | PEKING UNIVERSITY SHENZHEN GRADUATE SCHOOL (CN) | 2023-02-14 | — | — | US | disclosed |
| CN-110381918-B | Cosmetic composition | ELC 管理有限责任公司 | 2022-08-30 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11578060-B2 | JAK3 selective inhibitor | JAK3, JAK1, JAK2 | PRKCB 503/4885CDK4 506/4885CCND1 930/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.