Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCB | P05771 | 7/20 | 0.65 |
| ▸ | CDK4 | P11802 | 3/20 | 0.65 |
| ▸ | CCND1 | P24385 | 3/20 | 0.65 |
| ▸ | CDK2 | P24941 | 3/20 | 0.65 |
| ▸ | PRKCA | P17252 | 2/20 | 0.65 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.65 |
| ▸ | PRKACA | P17612 | 2/20 | 0.65 |
| ▸ | PRKACG | P22612 | 2/20 | 0.65 |
| ▸ | PRKACB | P22694 | 2/20 | 0.65 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.65 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.65 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.65 |
| ▸ | ABL1 | P00519 | 2/20 | 0.65 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.65 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.65 |
| ▸ | PRKCG | P05129 | 1/20 | 0.65 |
| ▸ | CDK1 | P06493 | 1/20 | 0.65 |
| ▸ | PIM1 | P11309 | 1/20 | 0.65 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.65 |
| ▸ | PRKCH | P24723 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29771997 | 1.00 | PRKCB (0.65) | PRKCBCDK4CCND1CDK2PRKCA | |
| Indazole SCHEMBL28147212 | 0.85 | PRKCB (0.49) | PRKCBCDK4CCND1CDK2PRKCA | |
| Ro-316233 SCHEMBL624896 | 0.79 | PRKCB (1.00) | PRKCBCDK4CCND1CDK2PRKCA | |
| Ro-316233 SCHEMBL29373011 | 0.79 | PRKCB (1.00) | PRKCBCDK4CCND1CDK2PRKCA | |
| SCHEMBL7951074 | 0.79 | PTPN1 (0.73) | PRKCBCDK4CCND1CDK2PRKCA | |
| SCHEMBL27866859 | 0.79 | PIK3CD (0.45) | PRKCBCDK4CCND1CDK2PRKCA | |
| SCHEMBL5879200 | 0.78 | CDK4 (0.46) | PRKCBCDK4CCND1CDK2PRKCA | |
| SCHEMBL5879319 | 0.78 | CDK4 (0.49) | PRKCBCDK4CCND1CDK2PRKCA | |
| SCHEMBL5879170 | 0.78 | F7 (0.45) | PRKCBCDK4CCND1CDK2PRKCA | |
| SCHEMBL5879255 | 0.78 | IGF1R (0.50) | PRKCBCDK4CCND1CDK2PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117276670-A | Lithium ion battery electrolyte and lithium ion battery | 湖州耀宁固态电池研究院有限公司 | 2023-12-22 | — | — | CN | claimed |
| CN-112575449-B | Polypropylene non-woven fabric with antibacterial property and preparation method thereof | 广州市新君发无纺布制品包装材料有限公司 | 2022-05-13 | — | — | CN | claimed |
| CN-112575449-A | Polypropylene non-woven fabric with antibacterial property and preparation method thereof | 广州市新君发无纺布制品包装材料有限公司 | 2021-03-30 | — | — | CN | claimed |
| CN-108431209-A | Derived and mature hepatocyte types of liver stem cells and uses thereof | 新加坡科技研究局 | 2018-08-21 | — | — | CN | claimed |
| CN-106188007-B | A kind of 3- piperidyls -4- indolylmaleimides class compounds and its preparation and application | 东华大学 | 2018-08-14 | — | — | CN | claimed |
| CN-108264503-A | A kind of preparation method of 3- Indolylmaleimide compounds | 东华大学 | 2018-07-10 | — | — | CN | claimed |
| CN-106188007-A | A kind of 3 piperidyl 4 indolylmaleimides compounds and preparation thereof and application | 东华大学 | 2016-12-07 | — | — | CN | claimed |
| CN-101835486-A | Pharmaceutical compositions for treating wounds and related methods | HEALOR LTD | 2010-09-15 | — | — | CN | claimed |
| US-20040220202-A1 | Neuroprotective and anti-proliferative compounds | AEGERA THERAPEUTICS INC. (CA) | 2004-11-04 | — | — | US | claimed |
| US-20040102467-A1 | Neuroprotective and anti-proliferative compounds | AEGERA THERAPEUTICS INC. (CA) | 2004-05-27 | — | — | US | claimed |
| WO-2003104482-A1 | SIGNALS AND MOLECULAR SPECIES INVOLVED IN SENESCENCE | METABOLIC ENGINEERING LABORATORIES CO., LTD. (KR) | 2003-12-18 | — | — | WO | claimed |
| EP-1283836-A2 | NEUROPROTECTIVE AND ANTI-PROLIFERATIVE COMPOUNDS | Aegera Therapeutics Inc. (CA) | 2003-02-19 | — | — | EP | claimed |
| WO-2001087887-A2 | NEUROPROTECTIVE AND ANTI-PROLIFERATIVE COMPOUNDS | AEGERA THERAPEUTICS INC. (CA) | 2001-11-22 | — | — | WO | claimed |
| EP-0397060-A2 | Maleinimide derivatives and their use as medicines | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1990-11-14 | — | — | EP | claimed |
| JP-2306974-A | — | — | None | — | — | JP | disclosed |
| CN-117276670-A | Lithium ion battery electrolyte and lithium ion battery | 湖州耀宁固态电池研究院有限公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-117276670-A | Lithium ion battery electrolyte and lithium ion battery | 湖州耀宁固态电池研究院有限公司 | 2023-12-22 | — | — | CN | disclosed |
| US-5380746-A | Bis-(1H-indol-3-YL)-maleinimide derivatives, processes for the preparation thereof and pharmaceutical compositions containing them | GOEDECKE AKTIENGESELLSCHAFT (DE) | 1995-01-10 | — | — | US | disclosed |
| JP-H02306974-A | MALEINIMIDE DERIVATIVE AND ITS USE AS MEDICINE | GOEDECKE AG | 1990-12-20 | — | — | JP | disclosed |
| EP-0397060-A2 | Maleinimide derivatives and their use as medicines | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1990-11-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040220202-A1 | Neuroprotective and anti-proliferative compounds | NLN, MKI67, BDNF | PRKCB 1602/4885CDK4 47/4885CCND1 106/4885 |
| US-20040102467-A1 | Neuroprotective and anti-proliferative compounds | MKI67, NLN, BDNF | PRKCB 1519/4885CDK4 50/4885CCND1 92/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.