Docusate

Docusate

SCHEMBL29772

CCCCC(CC)COC(=O)CC(C(=O)OCC(CC)CCCC)S(=O)(=O)[O-].CCCCC(CC)COC(=O)CC(C(=O)OCC(CC)CCCC)S(=O)(=O)[O-].[Ca+2]

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Docusate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MMP8 known ✓ P22894 1/20 0.35
RECQL P46063 1/20 0.78
CYP3A4 P08684 5/20 0.56
TSHR P16473 3/20 0.56
TDP1 Q9NUW8 2/20 0.56
ATM Q13315 1/20 0.56
ALDH1A1 P00352 7/20 0.44
CA2 P00918 4/20 0.44
LMNA P02545 4/20 0.40
MAPK1 P28482 3/20 0.40
HSD17B10 Q99714 1/20 0.40
PRSS1 P07477 1/20 0.39
PRSS2 P07478 1/20 0.39
PRSS3 P35030 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
MMP9 P14780 1/20 0.35
MMP14 P50281 1/20 0.35
CA1 P00915 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Docusate SCHEMBL11580011 0.99 RECQL (0.76) RECQLCYP3A4TSHRTDP1ATM
Docusate SCHEMBL31128363 0.97 RECQL (0.78) RECQLCYP3A4TSHRTDP1ATM
Docusate SCHEMBL13727352 0.97 RECQL (0.78) RECQLCYP3A4TSHRTDP1ATM
Docusate SCHEMBL61043 0.97 RECQL (0.78) RECQLCYP3A4TSHRTDP1ATM
Docusate SCHEMBL9722552 0.97 RECQL (0.78) RECQLCYP3A4TSHRTDP1ATM
Docusate SCHEMBL7262160 0.97 RECQL (0.78) RECQLCYP3A4TSHRTDP1ATM
Docusate SCHEMBL2310067 0.97 RECQL (0.78) RECQLCYP3A4TSHRTDP1ATM
Docusate SCHEMBL4113 0.97 RECQL (0.78) RECQLCYP3A4TSHRTDP1ATM
Docusate SCHEMBL3041223 0.97 RECQL (0.78) RECQLCYP3A4TSHRTDP1ATM
Docusate SCHEMBL23781730 0.96 RECQL (0.76) RECQLCYP3A4TSHRTDP1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2571 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4706393-A2 STABLE HERBICIDAL COMPOSITIONS UPL Corporation Limited (MU) 2026-03-11 EP claimed
EP-3970492-B1 STABLE HERBICIDAL COMPOSITIONS UPL CORPORATION LTD (MU) 2026-01-21 EP claimed
WO-2025202951-A1 COMPOSITION OF CLOTRIMAZOLE VAGINAL FILM AND PROCESS FOR PREPARATION THEREOF HETERO HEALTHCARE LIMITED (IN) 2025-10-02 WO claimed
US-20250114314-A1 COMPOSITION AND METHOD FOR TREATING MENSTRUATION RELATED SYMPTOMS HARRISON MARGO (US) 2025-04-10 US claimed
CN-116496767-B Wetting agent and preparation method and application thereof 中国石油化工股份有限公司 2024-07-19 CN claimed
US-20230363386-A1 STABLE HERBICIDAL COMPOSITIONS UPL EUROPE LTD (GB) 2023-11-16 US claimed
CN-114736144-B Industrial preparation method of docusate calcium 武汉百科药物开发有限公司 2023-10-13 CN claimed
US-20230273146-A1 SAMPLE HANDLING FOR DIAGNOSTICS QSM DIAGNOSTICS INC (US) 2023-08-31 US claimed
CN-116496767-A Wetting agent and preparation method and application thereof 中国石油化工股份有限公司 2023-07-28 CN claimed
CN-116437808-A Stable herbicidal compositions UPL有限责任公司 2023-07-14 CN claimed
EP-0026047-B1 PROCESS FOR POLYMERIZING FORMALDEHYDE UBE INDUSTRIES, LTD. (JP) 1984-04-04 EP claimed
EP-0028499-B1 PROCESS FOR POLYMERIZING FORMALDEHYDE UBE INDUSTRIES, LTD. (JP) 1984-02-01 EP claimed
US-4357934-A Method of treating male infertility THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) 1982-11-09 US claimed
US-4352923-A METAL CHELATE ADSORBED ON POLYOXYMETHYLENE GLYCOL AS CATALYST UBE INDUSTRIES, LTD. (JP) 1982-10-05 US claimed
US-4332930-A CATALYZED POLYOXYMETHYLENE PREPARATION IN THE PRESENCE OF A METAL SALT UBE INDUSTRIES, LTD. (JP) 1982-06-01 US claimed
EP-0032825-A2 Stabilized solutions of dioctyl calcium sulfosuccinate in corn oil MALLINCKRODT, INC.(a Missouri corporation) (US) 1981-07-29 EP claimed
EP-0028499-A1 Process for polymerizing formaldehyde UBE INDUSTRIES, LTD. (JP) 1981-05-13 EP claimed
EP-0026047-A1 Process for polymerizing formaldehyde UBE INDUSTRIES, LTD. (JP) 1981-04-01 EP claimed
US-4196200-A COMPLEXING, FEEDS AMERICAN CYANAMID COMPANY (US) 1980-04-01 US claimed
US-4070456-A CRYSTALLIZATION RESISTANT AMERICAN CYANAMID COMPANY (US) 1978-01-24 US claimed