Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Docusate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.78 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Docusate SCHEMBL7262160 | 0.97 | RECQL (0.78) | RECQLCYP3A4TSHRTDP1ATM | |
| Docusate SCHEMBL9722552 | 0.97 | RECQL (0.78) | RECQLCYP3A4TSHRTDP1ATM | |
| Docusate SCHEMBL29772 | 0.97 | RECQL (0.78) | RECQLCYP3A4TSHRTDP1ATM | |
| Docusate SCHEMBL3041223 | 0.97 | RECQL (0.78) | RECQLCYP3A4TSHRTDP1ATM | |
| Docusate SCHEMBL2310067 | 0.97 | RECQL (0.78) | RECQLCYP3A4TSHRTDP1ATM | |
| Docusate SCHEMBL31128363 | 0.97 | RECQL (0.78) | RECQLCYP3A4TSHRTDP1ATM | |
| Docusate SCHEMBL4113 | 0.97 | RECQL (0.78) | RECQLCYP3A4TSHRTDP1ATM | |
| Docusate SCHEMBL13727352 | 0.97 | RECQL (0.78) | RECQLCYP3A4TSHRTDP1ATM | |
| Docusate SCHEMBL23781730 | 0.96 | RECQL (0.76) | RECQLCYP3A4TSHRTDP1ATM | |
| Docusate SCHEMBL22588821 | 0.96 | RECQL (0.76) | RECQLCYP3A4TSHRTDP1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1927 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4706393-A2 | STABLE HERBICIDAL COMPOSITIONS | UPL Corporation Limited (MU) | 2026-03-11 | — | — | EP | claimed |
| EP-3970492-B1 | STABLE HERBICIDAL COMPOSITIONS | UPL CORPORATION LTD (MU) | 2026-01-21 | — | — | EP | claimed |
| WO-2025202951-A1 | COMPOSITION OF CLOTRIMAZOLE VAGINAL FILM AND PROCESS FOR PREPARATION THEREOF | HETERO HEALTHCARE LIMITED (IN) | 2025-10-02 | — | — | WO | claimed |
| US-20230363386-A1 | STABLE HERBICIDAL COMPOSITIONS | UPL EUROPE LTD (GB) | 2023-11-16 | — | — | US | claimed |
| WO-2022058748-A1 | STABLE HERBICIDAL COMPOSITIONS | UPL Corporation Limited (MU) | 2022-03-24 | — | — | WO | claimed |
| EP-3970492-A1 | STABLE HERBICIDAL COMPOSITIONS | UPL Corporation Limited (MU) | 2022-03-23 | — | — | EP | claimed |
| CN-114042067-A | Amoxicillin sodium for injection and preparation method thereof | 江西利德菲生物药业有限公司 | 2022-02-15 | — | — | CN | claimed |
| US-20210361663-A1 | Formulations of Antiviral Compounds | MERCK SHARP & DOHME CORP. (US) | 2021-11-25 | — | — | US | claimed |
| CN-112089844-A | Methods and compositions comprising desmopressin in combination with an M3 receptor antagonist | 清远市人民医院 | 2020-12-18 | — | — | CN | claimed |
| US-20200114012-A1 | METHOD FOR PRODUCING A LIQUID COMPOSITION | UNIV LIVERPOOL (GB) | 2020-04-16 | — | — | US | claimed |
| EP-0656965-B1 | LOW FUME FINISH FOR WET AIT-JET TEXTURING | DU PONT (US) | 1996-04-17 | — | — | EP | claimed |
| EP-0746342-A4 | BIODEGRADABLE CONTROLLED RELEASE MELT-SPUN DELIVERY SYSTEM | FUISZ TECHNOLOGIES LTD (US) | 1996-01-11 | — | — | EP | claimed |
| WO-1995017174-A1 | PROCESS FOR MAKING LAXATIVES CONTAINING DIOCTYL SULFOSUCCINATE | THE PROCTER & GAMBLE COMPANY (US) | 1995-06-29 | — | — | WO | claimed |
| EP-0656965-A1 | LOW FUME FINISH FOR WET AIT-JET TEXTURING. | DU PONT (US) | 1995-06-14 | — | — | EP | claimed |
| US-5350529-A | Polyoxyethylene nonionic emulsifier, ester, anionic surfactant | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-09-27 | — | — | US | claimed |
| WO-1994005847-A1 | LOW FUME FINISH FOR WET AIT-JET TEXTURING | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-03-17 | — | — | WO | claimed |
| WO-1993024154-A1 | BIODEGRADABLE CONTROLLED RELEASE MELT-SPUN DELIVERY SYSTEM | FUISZ TECHNOLOGIES, LTD. (US) | 1993-12-09 | — | — | WO | claimed |
| US-4196200-A | COMPLEXING, FEEDS | AMERICAN CYANAMID COMPANY (US) | 1980-04-01 | — | — | US | claimed |
| EP-0003644-A1 | Animal feed supplements containing antibiotic trans-BM 123-gamma and process for making same | AMERICAN CYANAMID COMPANY (US) | 1979-08-22 | — | — | EP | claimed |
| US-4075134-A | EMULSION POLYMERIZATION METHOD FOR PREPARING MICROSPHERES HAVING LIQUID CENTER AND SEAMLESS RIGID WALLS | THE DOW CHEMICAL COMPANY (US) | 1978-02-21 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200114012-A1 | METHOD FOR PRODUCING A LIQUID COMPOSITION | LIPA, LIPC, CEL | RECQL 2942/4885CYP3A4 1748/4885TSHR 4689/4885 |
| US-20210361663-A1 | Formulations of Antiviral Compounds | GYS2, VIM, WARS1 | RECQL 261/4885CYP3A4 82/4885TSHR 4758/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.